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Nutrition

How safe is intermittent fasting?

healthtostBy healthtostFebruary 9, 2024No Comments5 Mins Read
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How Safe Is Intermittent Fasting?
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Eating every other day can raise your cholesterol.

Is are there any downsides to fasting every other day? For example, it can I am going Does going all day without eating affect your ability to think clearly? Surprisingly, as I discuss in my video Is alternate day intermittent fasting safe?, the results appear to be “doubtful”. Some studies show no measurable effects, and those that do fail to agree on which cognitive domains are affected. Can cycles of fasting and feasting cause eating disorder-like behaviors such as binge eating? So far, there have been no harmful psychological effects were found. In fact, there may be some benefit. However, studies that have specifically put this to the test are excluded people with a documented history of eating disorders, for whom results may vary.

What about bone health? There was no change in bone mineral density famous after six months of intermittent fasting despite a weight loss of about 16 kg, which would normally result in reduced bone mass. However, the researchers observed no skeletal changes in the control group either, and they lost a similar amount of weight using continuous caloric restriction. They suggested this is because both groups tended to be “more physically active than the average obese American,” taking about 1,000 to 2,000 more steps per day.

Proponents of intermittent fasting I suggest It may protect lean body mass better, but most of the intermittent trials have are employed less accurate methods of analyzing body composition, while the majority of ongoing calorie restriction trials used “much more accurate techniques.” So, to this day, it is is it is unclear whether there is a difference in maintaining lean mass.

Improvements in blood pressure and triglycerides have been noted famous in intermittent fasting regimens, although this is thought to be due to the reduction in body fat, as the effect appears to be ‘dependent on the amount of weight lost’. Alternate fasting can also improve artery function, as you can see in the chart below and at 1:55 in my videoalthough yes depend about what you eat on your non-fasting day. For study participants randomized to an alternate-day diet high in saturated fat, their arterial function worsened despite a ten-pound weight loss, while it improved, as expected, in the low-fat group. The reduction in arterial function is thought to be due to the pro-inflammatory nature of saturated fat.


There was a concern lifted up on the effects of alternate day fasting on cholesterol. After 24 hours without food, LDL cholesterol can temporarily blow up, but that’s probably because so much fat is released into the system from fasting. As you can see in the chart below and at 2:33 in mine videoa direct negative effect on carbohydrate tolerance may stem from the same phenomenon—the repeated increases in free fat floating around in the bloodstream. After a few weeks, however, LDL levels begin to rise fall as the weight is removed. However, results from the largest and longest alternate-day fasting trial have given I pause.


A hundred obese men and women were randomized into one of three groups: modified alternate-day fasting (25 percent of their baseline calories on fasting days and 125 percent calories on eating days), continuous, daily calorie restriction (75 percent of baseline), or a control group that had instructed to maintain a regular diet. So for those entering the trial eating 2,000 calories a day, they would continue to eat 2,000 calories a day in the control group. The calorie restriction group would get 1,500 calories each day, and the intermittent restriction group would alternate between 500 calories one day and 2,500 calories the next.

As you can see in the chart below and at 3:32 in mine videowith the same total, average, prescribed calorie reduction in the two weight loss groups, both lost about the same weight, but, surprisingly, the cholesterol results were different. In the continuous calorie restriction group, LDL levels decreased as expected compared to the control group as the pounds dropped.

But, in the modified alternate day fasting group, they didn’t, as you can see below, and at 3:55 in my video. At the end of time, LDL cholesterol in the intermittent fasting group it is done is 10 percent higher than in the constant calorie restriction group—despite the same loss of body fat. Since LDL cholesterol is a primary causative risk factor for heart disease, our number one killer—or is even the primary risk factor — that strikes major blow against alternate day fasting. If you want to try it anyway, I’d advise monitoring your cholesterol to make sure it’s coming down with your weight.


If you are diabetic, you should talk with your doctor about adjusting your medication for any dietary changes, including fasting of any duration. Even with preemptive tapering of medication, advice to stop fasting immediately if blood sugars fall too low, and weekly medical supervision, people with type 2 diabetes who fasted even just two days a week were twice as likely to suffer hypoglycemic episodes in compared to non-fasting subjects. control team. We still don’t know the best way to modify blood sugar medications to prevent blood sugar from falling too low on fasting days.

Even fasting for just one day can be significant slow the clearance of certain drugs (such as the blood-thinning drug Coumadin) or increasing the clearance of others (such as caffeine). Fasting for 36 hours can reduce your caffeine intake by 20%. So consulting your doctor before fasting is an especially good idea for anyone taking any kind of medication.

If you missed it, check it out Alternate Day Intermittent Fasting Trial.

So with equivocal cognitive, lean mass, and bone results, plus these cholesterol findings, I wouldn’t recommend alternating fasting days for weight loss, but weight loss isn’t the only thing this diet is supposed to do. Checkout Does intermittent fasting increase human life expectancy?.

For other types of intermittent fasting, total fasting, and more about fasting, see the related videos below.

fasting intermittent safe
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New method identifies key proteins that trigger harmful immune responses

April 6, 2026

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