Author: healthtost
Targeted therapy with the RAS inhibitor daraxonrasib showed the potential to improve patient outcomes over current standard treatments for patients with RAS-mutated pancreatic cancer, according to results of a Phase 1/2 trial led by investigators at The University of Texas MD Anderson Cancer Center. The study, published today in The New England Journal of Medicineled by David Hong, MD, vice president of Investigational Cancer Therapeutics. Thirty-eight patients received 300 mg. daraxonrasib dose. The response rate was 29% and the median overall survival was 15.6 months, a significant improvement over historical response rates to second-line chemotherapy. “This trial provides a really…
If you’re looking for an effective fat-burning, muscle-toning routine that requires zero equipment and minimal space, 35-minute high-rep bodyweight workout challenge is one of the most effective ways to transform your physical condition. This style of training focuses on high repetitions, minimal rest and continuous movementshelping you build muscle endurance, improve cardiovascular health and burn calories fast—all from the comfort of your own home. Whether you’re a beginner looking to get started or a seasoned athlete looking to push your limits, this training challenge delivers. In this complete guide, you’ll learn how to structure training, the benefits of high-rep training,…
Quick Summary Learning how to insert a tampon doesn’t have to feel overwhelming. Start with a thin tampon and a plastic applicator, relax your pelvic muscles and aim towards your tail instead of straight. If you feel discomfort, stop and try again later. A properly placed tampon should not be visible at all. Pain usually means intensity, wrong angle or wrong size. Tampon use does not affect virginity and it is perfectly normal to need practice. Focus on comfort, not perfection. Understanding tampon use: A personal and practical guide A First Experience I still think about the first time I…
Kemari Copeland rose to fame in 2024 after obliterating Virginia Tech’s squat record by deadlifting an astounding 605 pounds — for 10 reps! And while the Hokies defensive lineman’s strong performance in the gym is building a solid foundation for football, he’s also working on the finer details like his strategy and body weight for Saturdays this season — and hopefully Sundays in the NFL. M&F sat down with the exciting lineman to learn more about his love of lifting and how he’s using the offseason to get ready for 2026 and beyond. And as he describes it, it was…
California teenagers consistently perceive cannabis as less harmful than other commonly used substances, according to a new study that analyzes data from two large surveys of schools across the state. Shu-Hong Zhu, PhD, professor at the UC San Diego Herbert Wertheim School of Public Health and Human Longevity Science and co-authors, examined how teenagers view the risks of daily and occasional cannabis use compared to alcohol, nicotine vapor and cigarettes, based on responses from more than 175,20 students and 2,000 respondents. 2024. The findings show a clear and persistent pattern: cannabis is seen as the least harmful substance among respondents.…
This article was originally written by Whitney Crouch, RDN, CLT and has been updated by the Metagenics Editorial Team. Filling nutritional gaps in children’s diets Many children do not get enough important vitamins and minerals each day. This guide to children’s vitamins can help parents learn simple ways to fill these gaps. A large study, known as the National Health and Nutrition Examination Survey (NHANES), found a disturbing trend. Many children and adults eat less than the recommended amounts of vitamins A, C, D and E. They also consume less calcium and magnesium than recommended. 1 These results highlight the…
What is skinification? If you’ve seen this word in beauty articles, heard it on social media, or noticed it in product marketing, you may have wondered what it was. It sounds modern, a bit confusing and frankly, a bit made up! We’re here to tell you that this is a real term and it could make a real difference to how your skin looks and feels. Read on to learn more. What is Skinification? Skinification is the idea of treating other parts of your body the way you treat the skin on your face. This means thinking beyond your usual…
Quick Answer: What is sexology?Sexology is the scientific and interdisciplinary study of human sexuality, including behavior, relationships, identity, pleasure, and health. It combines psychology, biology, sociology and education to understand how people experience and express sexuality across the lifespan.ImportIf you’ve ever wondered what sexology really isyou are not alone.The field is growing rapidly, yet many people still associate it with outdated or narrow ideas about sex. In fact, sexology is one of the most complex and important fields of study in modern health and human behavior.It is at the intersection of science, relationships, culture and well-being. And for many professionals,…
Born from their own transformative experiences of motherhood, Ellie and Luiza are reshaping how parents prepare for birth and beyond. After seeing firsthand how many women felt unsupported, overwhelmed, or unheard during their first journeys into parenthood, they set out to create a more flexible, accessible, and deeply personalized approach to prenatal education and doula care. In this interview, they share how a chance connection turned into a creation New Birth Clubbecause pre-birth preparation is where their real strength lies and their mission is to help parents feel informed, confident and truly supported, no matter what path their birth…
Commonly used diabetes and obesity drugs show strong cardioprotective effects in high-risk patients, providing new impetus for their role in reducing cardiovascular deaths. Study: The long-term cardiovascular safety and efficacy of glucagon-like peptide-1 (GLP-1) receptor agonists in high-risk cardiovascular populations: a systematic review and meta-analysis. Image credit: Studio Romantic / Shutterstock.com In a recent study published in Cardiovascular Diabetes–Endocrinology Reports, Researchers evaluated the long-term cardiovascular safety and efficacy of glucagon-like peptide-1 receptor agonists (GLP-1RAs) in high-risk populations. The increasing cardiovascular burden and the expanding role of GLP-1 therapies Cardiovascular disease (CVD) causes more than 17.9 million deaths each year, making…