A new study funded by Mirvie, which is the first to evaluate the USPstF (USPstF) Task Force (USPstF) Task Force guidelines for the risk of pre -pricing and aspirin recipe in a single, representative, prospective population found, while high risk factors had sufficient value for the risk of Moderate risk – leading non -specific recommendations for the use of aspirin, a tool recognized by Asperine.
This 5684 participants’ co -coo study, which spread from the multicenter miracle of life’s perspective study, found that the guidelines found almost 89% of pregnancies at increased risk of preeclampsia. 70.3% were in the category of moderate risk, determined by the mother’s characteristics and broad demographic elements, including age, body mass index and race, while 18.5% were in the high risk category, which includes patients with conditions such as chronic hypertension or previous history.
The findings of the study indicate that the cloudiness of moderate risk factors can affect clinics’ decisions on daily aspirin recommendations. While 82% of women with high risk factor is recommended daily aspirin, only 37% of people with one or more moderate risk factors were given this recommendation. USPSTF, the American College of Obstetricians and Gynecologists (ACOG) and the Mother-Faith’s Medicine (SMFM) guidance to examine or suggest aspirin start between 12 to 28 weeks of pregnancy for pregnancies with moderate risk factors.
“The detection of 9 of 10 women, as at risk, does not help and overload care groups and pregnant patients,” said Dr. Thomas McElrath, vice president of Mirvie’s clinical development and a medical mother in Mass Brigham, as well as the head of the study. “Doctors may be reluctant to prescribe aspirin when the majority of their patients fall into moderate risk.
Most pregnant women in the study (70.3%) fell into the moderate risk category using the USPSTF guidelines, but had one or more moderate risk factors and no high risk factor was predicted to the risk of preeclampsia. Among people with 2 or more moderate risk factors, but without high risk factor, the sensation was associated with moderate risk of preeclampsia (RR, 1.48, 95% CI, 1.35-1.62, p <.001). There was little or no relationship with obesity (RR, 1.11, 95% CI, 1.01-1.22, P = .048), Black Race (RR, 0.95, 95% CI, 0.80-1.14, P = .63) and advanced age (RR, 0.79, 95% CI, 0.65-0.96, P = P =. .02).
“The rates of preeclampsia in the US have doubled over the last 15 years and continue to rise without end,” said Kara Boeldt, survivors and founder and executive director of Endpreeclampsia.org. “The introduction of the USPSTF guidelines in 2021 did nothing to reverse the path to the rise of preeclamps. Risk of preeclable with a simple blood test during pregnancy.
The findings of this important study confirm the need for clear, objective prediction of preeclable risk measures, to motivate preventive care. “
Maneesh Jain, CEO and co -founder, Mirvie
“With innovation like ECCOMPASS ™, we can now provide precautionary care to the right patients at the right time and rates of premature birth.”
Source:
Magazine report:
McElrath, TF, et al. (2025) The utility of the US Task Force Previous Services for the assessment of the risk of preeclampsia and the protection of aspirin. Open the Jama Network. Doi.org/10.1001/jamanetworkopen.2025.21792.
