Self-syllable tests for human papillary (HPV) were more than doubled the involvement of cervical cancer among US women who had not undergone non-submarine, according to a first study by researchers at the University of Texas MD Anderson Cancer Center.
In the real world, randomized, Prestis study, published today in Jama Internal Medicine41% of people who received self-collection tests and a telephone reminder participated in the control of cervical cancer, compared to only 17% of those who received only phone reminder. Add patient navigation support in self-collection tests and the telephone reminder increased further the participation rates to 47%.
Too many women, especially those who are uninsured, live in rural areas or come from marginalized and inadequate communities, are not taken sorting for cervical cancer. These results show that self-collection tests could be a solution to increase access to examination and, in turn, reducing the weight of cervical cancer in the US ”
Jane Montealegre, Ph.D., Head writer, Associate Professor of Behavioral Science
In May 2025, the Food and Drug Administration approved the first home screening test on cervical cancer, a disease that affects almost 13,000 women a year. While HPV vaccination and office control have led to significant reductions in cervical cancer rates, inequalities in results, especially for women and those who are in the provinces of farm and low income, continue.
Between February 2020 and August 2023, the Prestis study records about 2,500 women aged 30-65 years from the Houston region. Most (94%) came from ethnic/racial disadvantage populations and 56% were covered by a financial aid program funded by the State. Patients received one of the three intervention approaches: 1) Phone reminder for clinic -based control. 2) Phone reminder with self -service test with mail. and 3) a telephone reminder with self-collection test and patient navigation. The results on the audit participation were collected in six months.
Researchers also found that more than 80% of women in self-collection groups returned their kits, providing further details of preference and improved suitability of this approach to this patient population.
“As self-collection tests are made available in the US, it is vital to collect data to guide how they extend. We want to ensure that they are available in clinics and health centers that take care of people who often have the most difficult time to have access to health care,” he said. “With the abolition of barriers, we hope that we can improve the recruitment of sorting tests based on evidence and make significant progress against this preventive disease.”
The next steps for researchers will study how to integrate HPV Self-Collection tests into different primary care settings.
The restrictions of this study include the results of the Covid-19 pandemic, the vague reasons for refusing to participate and the obstacles around the mission of kits to the houses of the peoples. The test also did not evaluate the differences in the types of monitoring of the appointments that patients need if they try positive for HPV.
This study was supported by grants by the National Institutes of Health, including the National Institute of Minorities and the National Institute of Cancer (R01MD30175, P30CA016672, P30CA125123, P30CA138313).
Source:
Magazine report:
Montealegre, Jr, et al. (2025). Self -service for screening cervical cancer in a safety setting: the randomized Prestis clinical trial. Jama Internal Medicine. Doi.org/10.1001/jamainternMed.2025.2971.
