Author: healthtost

This year’s European Antibiotic Awareness Day (EAAD) focuses on the objectives outlined in the 2023 Council Recommendation to strengthen efforts in the European Union (EU) against antimicrobial resistance in a One Health approach. These recommendations set a 2023 target to reduce overall antibiotic consumption (community and hospital sector combined) by 20%, using consumption data from 2019 as a baseline. Antibiotic consumption in the community accounts for approximately 90% of total use. This means that a substantial and consistent reduction in antibiotic use in this area will be crucial to achieving the set 2030 targets aimed at preventing and reducing antimicrobial…

Researchers at the University of Wisconsin-Madison have identified a protein key to the development of a type of brain cell believed to play a role in disorders such as Alzheimer’s and Parkinson’s diseases, and used the discovery to grow neurons from stem cells for the first time. Stem cell-derived norepinephrine neurons of the type found in a part of the human brain called the locus coeruleus could enable research into many psychiatric and neurodegenerative diseases and provide a tool for developing new ways to treat them. Yunlong Tao, a researcher at Nanjing University in China who was a research professor…

Small molecules called immunomodulators can help create more effective vaccines and stronger immunotherapies to treat cancer. But finding the molecules that trigger the right immune response is difficult – the number of drug-like small molecules has been estimated at 1060much higher than the number of stars in the visible universe. In a possible first for the field of vaccine design, machine learning guided the discovery of new molecules that enhance the immune pathway and found a specific small molecule that could outperform the best immunomodulators on the market. The results are published in the journal Chemical Science. “We used artificial…