Author: healthtost

A polygenic, multi-condition risk report validated in US health systems could help clinicians identify inherited cardiovascular risk earlier, improve prevention strategies, and guide more personalized care. Study: Development and Validation of a Clinical Polygenic Risk Report in US-Based Health Systems for 8 Cardiovascular Diseases. Image source: ArtemisDiana / Shutterstock In a recent study published in Journal of the American College of Cardiology (JACC)investigators described the development and validation of integrated polygenic risk scores (PRS) for eight cardiovascular diseases using data from 245,394 All of Us participants (AOU) Research Program and 53,306 participants from the Mass General Brigham Biobank (MGBB). The…

It’s May Lupus Awareness Month.Did you know that the word “wolf” is Latin for wolf? We know it sounds random, but there is meaning behind the name. In the 13th century, a health care provider (HCP) said that the skin lesions from the disease looked like a wolf bite mark. Usually when people talk about lupus, they are referring to the most common type called systemic lupus erythematosus. “Systemic” means throughout your body and “erythematous” comes from the Greek word redmeaning red — a nod to the butterfly-shaped rash associated with the disease. While the name represents a few symptoms…

As an esthetician for nearly four decades, I believe the best way to get results is to be a part of my clients’ journey, both with hands-on professional treatments and a focused skincare routine. skin type (what I like to call an “Action Plan”) to continue the results at home. I’m starting a new series called “How I Did This” where I highlight a client who had tried it all but was only left confused with no real results. She had a fire that no one helped her put out…until she put her skin in my hands.Hormonal hyperpigmentation is one…

SMSNA receives and publishes “guest editorials” periodically. The current article was submitted by Mia Barnes, a freelance writer and researcher specializing in women’s health, wellness and healthy living. She is its Founder and Editor-in-Chief Body+Mind Magazine Noticing changes in your sexual function can be overwhelming. Clear and direct information is the best tool for maintaining health. Peyronie’s disease is a common and non-cancerous condition that doctors can treat. Scar tissue develops inside the penis, which usually leads to painful erections. Learn the early symptoms and steps to take to manage it properly. What is Peyronie’s disease? According to the American…

Billions of dollars worth of drugs have been pulled from the market for less carcinogenic contamination than is found in a single serving of grilled chicken. In 2018, one of the best-selling blood pressure drugs, valsartan—sold as Diovan—was I establish to be contaminated by the “probably carcinogenic” nitrosamine known as N-nitrosodimethylamine (NDMA). About 20 million people worldwide are believed to have been prescribed the drug contaminated with this cancer-risk contaminant it seems exceed that of many known strong carcinogens, such as asbestos, PCBs and benzo[a]pyrene. As I discuss in my video Cancer-causing NDMA in drugs (Zantac, metformin) and meatthe US…

I’ve been a fan of the ground mine since the early days of Cressey Sports Performance when we started implementing it into our clients’ and athletes’ programs.Now, I’m not going to sit here and say that Land Mine is a fitness and performance panacea. I like it and use it (often). But it’s not like it’s going to cut your 40 time by 0.7 seconds, add 50 pounds to your deadlift in a week, make it so your folks can cut diamonds, or give you the power of invisibility.That being said, there are many reasons why I dig it.Here are…

A targeted GLP-1-GIP-lanifibranor conjugate provided broad metabolic benefits in obese mice, indicating a potential new generation of multi-pathway therapies for obesity and type 2 diabetes. Study: GLP-1R-GIPR-PPARα/γ/δ quintuple agonism corrects obesity and diabetes in mice. Image credit: zimmytws / Shutterstock A recent study published in the journal Nature describes the creation of a novel single-molecule quintuple agonist designed to integrate incretin-mediated metabolic regulation with the anti-inflammatory effects and insulin-sensitizing properties of lanifibranor. In preclinical models, the compound demonstrated greater efficacy than semaglutide and glucagon-like peptide-1 receptor (GLP-1R) – glucose-dependent insulinotropic polypeptide receptor (GIPR) dual treatment, resulting in marked reductions in…

Simple, science-based ways to boost your energy, balance your mood, and restore your health this springAuthor: Roxane ShymkiwThere’s something about spring that naturally feels like a time to reset. Every year, I tell myself I’m going to do a full spring cleaning of my house, but honestly, the process is often more overwhelming than inspiring. This year, I decided to take a different approach, starting not with my environment, but with my diet. Why? Because what we eat does much more than just fuel the body. It directly affects our mood, energy, focus and resilience. Spring is the perfect opportunity…

The human body comes in different shapes and sizes, and one of the most common body shapes is the pear-shaped body. A pear-shaped body is characterized by wider hips and thighs, with a narrower waist and shoulders. This body type is also known as a triangle shape and is more common in women than men. If you have a pear-shaped body, it can be difficult to find the right exercise routine and diet that works for you. Various factors can affect a pear-shaped body, including genetics, hormones, and lifestyle. Genetics play an important role in determining your body shape, as…

A simple photo of a face can reveal more than appearance. This study shows how tracking subtle changes in facial aging over time could help predict survival and reshape cancer care. Study: Facial aging rate quantifies change in biological age to predict cancer outcomes. Image credit: hedgehog94/Shutterstock.com A study published in Nature communications examines the predictive ability of photo-based facial aging rate (FAR) for overall survival in cancer patients. Artificial intelligence-derived facial age as a measurable biological marker Rates of biological aging vary significantly between individuals and can influence cancer outcome regardless of chronological age. However, their clinical use remains…