The new findings question the belief that animal protein increases the risk of mortality, shows no harm to longevity and even a small effect of US adult cancer.
Study: Ordinary Animal and Plant Protein Recruits are not adversely linked to the risk of mortality associated with cancer: a Nhanes III analysis. Credit Picture: Victoria 1/Shutterstock.com
A recent study at Applied Physiology, Nutrition and Metabolism He explored the impact of the intake of protein and herbal herbal on mortality from all causes, cancer and cardiovascular disease (CVD). Researchers did not observe differential correlations between the risk of mortality and dietary proteins derived from plants and animals. They also found that the intake of animal proteins was associated moderately with a lower risk of cancer mortality.
Intake of proteins and health
In the US and Canada, the recommended dietary compensation (RDA) for proteins is set to 0.8 g of protein/kg/day for good health. However, the dietary protein varies within the accepted macronutrient distribution areas (AMDR) is several times higher than the RDA. There is no clear recommendation about how much dietary protein intake is beneficial, especially in the elderly population.
Research has shown that higher consumption of animal proteins increases the risk of cancer and CVD mortality. On the contrary, the intake of protein plants has been linked to higher health benefits and lower mortality risk. A previous study used the third national research on health and nutrition examination 1988-1994 (NHANES III), revealing the correlation between the highest protein intake and the significant increase in overall mortality. This study also showed that higher protein consumption could lead to four times more increased risk of cancer in adults aged 50-65 years. However, these results will vary depending on whether or not the protein consumed by plants.
Mechanically, the proposed effects that promote high protein intake cancer are associated with the 1-type insulin-type growth factor (IGF-1). A linear correlation has been documented between protein intake and IGF-1 circulation. Therefore, a lower protein intake can reduce the risk of mortality associated with IGF-1 and mortality of all causes. Interestingly, meta-analyzes have indicated a U-shaped relationship between IGF-1 and mortality, that is, the increased mortality risk in people with lower or higher IGF-1 levels.
Taking into account heterogeneous effects on the health effects of protein intake, more studies are needed to assess the relationship between the usual intake of protein and plants and cancer, as well as all the causes and risk of mortality from CVDs in adults of various age groups.
For the study
The current study examined whether the intake of animal proteins can increase the risk of mortality, especially in middle -aged adults and whether the intake of protein plants may be protective. Researchers also assume that IGF-1 circulation will not be associated with mortality.
NHANES III research data from 1988 to 1994 and protein recruitment data in all adults over 19 years of age were included. Initially, 15,937 participants were displayed. 7.483 were men and 8,454 were women. People with unreliable data, no surveillance reports and pregnant or female females were excluded.
Total calories, proteins, animal proteins, vegetable protein, total fats and carbohydrates were valued and formed using the Markov Monte Carlo (MCMC) multiple variable method. The nutrient content was assessed by linking food composition data provided by the USDA nutrient database for standard reference (SR). The risk models operated only with participants with a complete set of variables.
The National Assistant Assistant Assistant Funding funded the study, although the authors said the sponsor had no role in its design, analysis or interpretation.
Study findings
The current study showed that the intake of animal proteins was not associated with an increased risk of cancer, all causes or CVDs. However, age, smoking and sedentary lifestyle were recognized as expected risk factors for mortality of all causes in customized models. Regular consumption of animal proteins was associated with a moderate but significant correlation with cancer mortality.
There was no correlation between the usual consumption of vegetable proteins and the risk of mortality, or the risk of cancer mortality. The result remained unchanged, even when mortality, either for all causes, CVD or cancer, was determined in adults between the ages of 19 and 65 or those of 65 years.
Participants who consume herbal proteins did not have a correlation between the intake of proteins and the cause, CVD and the risk of cancer mortality when they were evaluated on a 5 or 10 g growth basis. There was no correlation with the mortality of all causes or CVD for animal proteins when evaluated on a 5 or 10 g growth basis. However, a significant reverse correlation was observed with cancer mortality. A simultaneous introduction of protein of animals and plants into the risk model showed similar results.
The current study did not observe any correlation between IGF-1 concentrations and the risk of mortality of all causes, cancer and CVD. The risk analysis (HR) in all adults has not shown a significant relationship between the usual protein intake and the risk of mortality of all causes, the risk associated with CVD or the risk of cancer mortality. There has been no change in HR between younger and older pigs for animal proteins or vegetable proteins for mortality of all causes, CVDs and cancer.
Unlike the previous findings of the study, this study did not find beneficial effects of mortality by increasing the consumption of vegetable proteins. A moderate but important protective relationship was observed between the usual intake of animal proteins and cancer mortality. Such a correlation was absent for the usual intake of vegetable protein.
Conclusions
The current study showed no correlation between animals or herbal proteins with a risk of mortality from all causes or CVDs. No correlation was observed between IGF-1 concentration and all causes, CVDs and cancer-related mortality even in the elderly population. Increasing the intake of animal proteins has shown a small but statistically significant reduction in cancer mortality.
The authors mentioned several limitations, including the lack of nutrients compared to the analysis. In addition, since the results of the IGF-1 were only associated with a population sub-section, this could underestimate the actual number of mortality events. Future research should include biomarkers and urine nitrogen to assess the effect of protein intake.
