Close Menu
Healthtost
  • News
  • Mental Health
  • Men’s Health
  • Women’s Health
  • Skin Care
  • Sexual Health
  • Pregnancy
  • Nutrition
  • Fitness
What's Hot

30 minutes Kettlebell Core Workouts to strengthen your abdomen

June 9, 2025

Semaglutide for Weight Loss – Summer Safety and Side Effects Guide

June 9, 2025

Teenagers and sexual education during the Covid-19 pandemic and beyond

June 9, 2025
Facebook X (Twitter) Instagram
  • About Us
  • Contact Us
  • Privacy Policy
  • Terms and Conditions
  • Disclaimer
Facebook X (Twitter) Instagram
Healthtost
SUBSCRIBE
  • News

    AI model detects brain tumors with high precision using epigenetic fingerprints

    June 8, 2025

    The new study warns long -term risks from germ transplants

    June 8, 2025

    Self-collection tests could be a solution to increase access to cervical cancer control

    June 7, 2025

    Preeclampsia associated with long -term brave disbelief and worsening the effects of stroke

    June 7, 2025

    In Axing’s MRNA contract, Trump delivers another blow to US bio -security, former officials say

    June 6, 2025
  • Mental Health

    Heart attack or panic attack? Why do young people call ambulances for non -managed stress

    June 7, 2025

    My journey, my development, my truth – uninterrupted

    June 6, 2025

    Why I am fighting for mental health change

    June 3, 2025

    Girls with painful periods are twice as high as their peers to have symptoms of anxiety or depression

    June 2, 2025

    Does psychiatric drug kill creativity? Rejecting Van Gogh’s myth

    May 29, 2025
  • Men’s Health

    30 minutes Kettlebell Core Workouts to strengthen your abdomen

    June 9, 2025

    Scientists identify genetic indications that connect air pollution to neurodegeneration

    June 7, 2025

    Do you want a stronger back? This Powerlifter’s secret weapon is a secret weapon

    June 7, 2025

    Chains, bands and greater profits: Guide to deal with resistance

    June 6, 2025

    Phil Stutz, True Magic & Healing Mankind: Useful tools for today’s World – Part 2: Universe 1 and Universe 2

    June 6, 2025
  • Women’s Health

    Making the connection between collagen and recovery from exercise

    June 8, 2025

    Alice Connors for purpose and progress

    June 4, 2025

    8 teenagers of vitamins must actually get

    June 4, 2025

    Reasons for frequent urination

    June 3, 2025

    Life with myalgian encephalomyelitis/chronic fatigue syndrome

    June 3, 2025
  • Skin Care

    Semaglutide for Weight Loss – Summer Safety and Side Effects Guide

    June 9, 2025

    10 signs it’s time to see an acne expert

    June 8, 2025

    11 Important facts for Botox Botox hood

    June 7, 2025

    Liposcopy: Is it right for you?

    June 7, 2025

    Ideas for father’s day and beyond

    June 4, 2025
  • Sexual Health

    Teenagers and sexual education during the Covid-19 pandemic and beyond

    June 9, 2025

    The odd rise of cases of syphilis to heterosexual men in the UK

    June 8, 2025

    The Role of Certified LGBTQ Certified Sexual Therapist – Sexual Health Alliance

    June 7, 2025

    How Pride paved the way for sexual well -being

    June 5, 2025

    Best male masturbation positions Female

    June 4, 2025
  • Pregnancy

    Love in Melbourne Australia – Tiffany Rose Maternity Blog UK

    June 8, 2025

    How to remain calm with high blood pressure during pregnancy?

    June 7, 2025

    Pink Stork’s flagship product – as shown in “Empowered by Meg Ryan”

    June 7, 2025

    You don’t have to know everything – only that before birth

    June 6, 2025

    Top 100 Names of Girls 2024

    June 5, 2025
  • Nutrition

    The busy mom’s driver for intestinal-brain connection

    June 7, 2025

    Healthy Banana Bread (Child Approved) Sarah Remat

    June 6, 2025

    The secret to the loss of persistent belly fat by registered dieticians

    June 5, 2025

    Why are you always tired and what to do

    June 5, 2025

    20 herbal and wonderful recipes with appetizers

    June 4, 2025
  • Fitness

    Creamy all the toast Avocado bagel (easy, salty breakfast!)

    June 8, 2025

    Men’s Health Month: Dealing longevity vacuum

    June 7, 2025

    Best 12 biceps exercises ranked: build larger and stronger weapons

    June 6, 2025

    Próximamente el 10 de junio: 25 minutes of train de Joel Freeman

    June 5, 2025

    The best weight counter to add to your home gym in your 2025

    June 5, 2025
Healthtost
Home»News»Study reveals altered protein rhythms linked to metabolic disorders in night shift workers
News

Study reveals altered protein rhythms linked to metabolic disorders in night shift workers

healthtostBy healthtostMay 9, 2024No Comments3 Mins Read
Facebook Twitter Pinterest LinkedIn Tumblr Reddit WhatsApp Email
Study Reveals Altered Protein Rhythms Linked To Metabolic Disorders In
Share
Facebook Twitter LinkedIn Pinterest WhatsApp Email

Just a few days on a night shift schedule spikes protein rhythms associated with blood glucose regulation, energy metabolism and inflammation, processes that can influence the development of chronic metabolic conditions.

The finding, from a study led by scientists at the University of Washington and the Pacific Northwest National Laboratory, provides new clues as to why night shift workers are more prone to diabetes, obesity and other metabolic disorders.

There are processes linked to the master biological clock in our brains that tell day is day and night is night, and other processes that follow rhythms set elsewhere in the body that tell night is day and day is night. When the internal rhythms are out of whack, you have this constant stress in your system that we think has long-term health consequences.”


Hans Van Dongen, senior study author, professor, WSU Elson S. Floyd College of Medicine

Although more research is needed, Van Dongen said the study shows that these disrupted rhythms can be seen in as little as three days, suggesting that early intervention to prevent diabetes and obesity is possible. Such an intervention could also help reduce the risk of heart disease and stroke, which is also elevated in night shift workers.

Posted on Journal of Proteome Research, the study involved a controlled laboratory experiment with volunteers placed in simulated evening or day shift schedules for three days. After their last shift, the participants stayed awake for 24 hours under constant conditions—lighting, temperature, posture, and food intake—to measure their internal biological rhythms without interference from outside influences.

Blood samples taken at regular intervals during the 24-hour period were analyzed to identify proteins present in blood-based immune system cells. Some proteins had rhythms closely tied to the master biological clock, which keeps the body on a 24-hour rhythm. The master clock is robust to altered shift schedules, so these protein rates did not change much in response to the night shift schedule.

However, most other proteins had significantly altered rates in night shift participants compared to day shift participants.

Looking more closely at the proteins involved in glucose regulation, the researchers observed an almost complete reversal of glucose rates in the night shift participants. They also found that the processes involved in insulin production and sensitivity, which normally work together to keep glucose levels in a healthy range, were no longer synchronized in the night shift participants. The researchers said this effect could be caused by insulin regulation trying to reverse the glucose changes caused by the night shift schedule. They said this may be a healthy response at the moment, as fluctuating glucose levels can damage cells and organs, but could be problematic in the long term.

“What we’ve shown is that we can actually see a difference in molecular patterns between volunteers with regular schedules and those with schedules that are not aligned with their biological clock,” said Jason McDermott, a computer scientist in PNNL’s Department of Biological Sciences. “The effects of this misalignment have not been characterized at this molecular level and in this controlled manner before.”

The researchers’ next step will be to study real workers to determine whether night shifts cause similar protein changes in long-term shift workers.

Source:

University of Washington

Journal Reference:

McDermott, JE, et al. (2024). Molecular-level dysregulation of insulin pathways and inflammatory processes in peripheral blood mononuclear cells by circadian misalignment. Journal of Proteome Research. doi.org/10.1021/acs.jproteome.3c00418.

altered Disorders linked metabolic night protein reveals rhythms shift study workers
bhanuprakash.cg
healthtost
  • Website

Related Posts

AI model detects brain tumors with high precision using epigenetic fingerprints

June 8, 2025

The new study warns long -term risks from germ transplants

June 8, 2025

Self-collection tests could be a solution to increase access to cervical cancer control

June 7, 2025

Leave A Reply Cancel Reply

Don't Miss
Men's Health

30 minutes Kettlebell Core Workouts to strengthen your abdomen

By healthtostJune 9, 20250

Looking to get your basic training at the next level in just 30 minutes? A…

Semaglutide for Weight Loss – Summer Safety and Side Effects Guide

June 9, 2025

Teenagers and sexual education during the Covid-19 pandemic and beyond

June 9, 2025

Creamy all the toast Avocado bagel (easy, salty breakfast!)

June 8, 2025
Stay In Touch
  • Facebook
  • Twitter
  • Pinterest
  • Instagram
  • YouTube
  • Vimeo
TAGS
Baby benefits body brain cancer care Day Diet disease exercise finds Fitness food Guide health healthy heart Life Loss Men mental Natural Nutrition Patients Pregnancy protein research reveals Review risk routine sex sexual Skin study Therapy Tips Top Training Treatment Understanding ways weight women Workout
About Us
About Us

Welcome to HealthTost, your trusted source for breaking health news, expert insights, and wellness inspiration. At HealthTost, we are committed to delivering accurate, timely, and empowering information to help you make informed decisions about your health and well-being.

Latest Articles

30 minutes Kettlebell Core Workouts to strengthen your abdomen

June 9, 2025

Semaglutide for Weight Loss – Summer Safety and Side Effects Guide

June 9, 2025

Teenagers and sexual education during the Covid-19 pandemic and beyond

June 9, 2025
New Comments
    Facebook X (Twitter) Instagram Pinterest
    • About Us
    • Contact Us
    • Privacy Policy
    • Terms and Conditions
    • Disclaimer
    © 2025 HealthTost. All Rights Reserved.

    Type above and press Enter to search. Press Esc to cancel.