Submitted by Metagenics Marketing Team
For women, hormones, energy, mood and sleep are deeply connected. When anxiety or bad sleep disturbs one, the whole system can be thrown out of balance. If you have ever felt exhausted but incapable of sleeping, your body’s hormonal response may be in the game.
How hormones affect sleep patterns
Hormones act as messengers of the body and when not synchronized, you may notice disorders in sleep standards, mood, energy levels and general well -being. Stress, in particular, can send cortisol levels, making it harder to relax and get quality sleep. The good news? You can break the circle. By understanding the connection between hormonal imbalance, sleep and anxiety, you can take small, important steps to restore balance and start feeling your best.1.2
Cortisol and anxiety: How it affects hormonal balance
Cortisol, often referred to as “hormone stress”, is produced by the adrenal glands and plays a key role in body response to stress. While short-term cortisol spikes help alert, chronic stress can lead to persistently high levels of cortisol-causing weight gain, disturbed sleep and mood changes.3 If you wake up to feel tired or wired at night, cortisol could be the culprit.
Melatonin and Sleep: The Circadian rhythm hormone
Melatonin, produced by the epiphany gland, regulates the sleep-fall cycle. Its production increases in the evening, helping you feel drowsiness. But when the anxiety or screen time disturbs melatonin production, falling and sleeping becomes difficult.4 Supporting the natural levels of melatonin is the key to better rest.
Female hormones and sleep: estrogen and progesterone
Estrogen and progesterone not only affect your cycle – they also affect how well you sleep. Estrogen helps to regulate serotonin, which supports restful sleep, while progesterone acts as a natural sedative. When these levels of hormones fall (such as before the period or during menopause), you may notice insomnia, night sweats or mood disorders.5
Thyroid hormones and sleep problems in women
Your thyroid also plays a role in sleep. Hyperthyroidism can lead to insomnia and night sweats, while hypothyroidism can cause fatigue during the day and excessive sleep. If your sleeping problems come with weight changes or fatigue, consider checking your thyroid levels.6.7

Hunger hormones, weight and sleep
Sleep affects insulin, leptin and ghrelin – hormones that regulate hunger and completeness. Bad sleep can cause leptin to decline (which marks satiety) and ghrelin (which marks hunger) to increase. This often leads to longing and weight gain, creating another stress for your hormonal system.8
HGH and restorative sleep
Human growth hormone (HGH), necessary for tissue repair and recovery, is mainly released during deep sleep. Without quality rest, HGH levels reduce metabolism, recovery and aging.8
How stress and sleep loss create a hormonal imbalance loop
Chronic stress increases cortisol, which disrupts the balance of melatonin and estrogen. In turn, bad sleep causes further stress on the body – which invokes stress, fatigue and a cycle that is difficult to break.
The common signs of hormonal imbalance include9:
- Fatigue and brain fog
- Anxiety or changes in mood
- Weight gain
- Sleep disorders
- Impaired immunity
Lifestyle tips to improve sleep and hormone support
- Keep a normal time to sleep and awakening10
- Limit the Blue Light Exhibition at night
- Practical attention or breathing exercises daily1
- Eat balanced meals to stabilize blood sugar8
- Integrate the rich in magnesium food and loose teas
Supplements for hormonal balance and better sleep
Some science -backed supplements can help restore balance, especially when used in parallel with changes in healthy lifestyle:
- Naturally balanced: Icebredness, fatigue, bloating, sleep and cravings*
- ESTROVERA®: Clinically proves to reduce hot flashes and improves sleep quality during menopause*
- Rapid stress relief: It has customized factor in reducing cortisol and will help you relax*
- Recharge overnight: Supports rest and night recovery with melatonin and relaxing herbs*
Explore Herwellness â„¢ Collection
Herwellness â„¢ Metagenics’ offers solutions supported by science for The anxiety, sleep and health of women. Whether you navigate PMS, Perimenopause, or daily stress, explore physical support for every stage of life.
Frequently questions
Which supplements are good for hormonal balance?
Can stress cause hormonal imbalance?
Yes. Chronic stress increases cortisol, which disrupts other levels of hormones, including melatonin, estrogen and progesterone.
What are the symptoms of hormonal sleep problems?
Common signs include the difficulty falling or staying sleeping, night sweats, mood changes and fatigue.
Reports:
- Yale Medicine. (nd). Women: Do your hormones keep you at night?
- News Medicine. (nd). Sleep and hormones.
- Times. (nd). How to eat and exercise cortisol balancing – and why it matters.
- Health.com. (nd). Melatonin vs magnesium for sleep: Which one is right for you?
- Alzueta, E., & Baker, FC (2023). The menstrual cycle and sleep. Clinics of Medical Sleep, 18(4), 399-413.
- News Medicine. (nd). Sleep and hormones.
- Endocrine MDS. (nd). 7 signs of early warning of thyroid issues.
- Healthline. (nd). How sleep can affect your hormone levels.
- Healthline. (nd). Hormonal insomnia: symptoms, causes and treatments.
- Metagonal. (2018, April 12). How to Sleep: Tips for better rest and recovery.