Close Menu
Healthtost
  • News
  • Mental Health
  • Men’s Health
  • Women’s Health
  • Skin Care
  • Sexual Health
  • Pregnancy
  • Nutrition
  • Fitness
What's Hot

How to move to a city can add 1,100 steps to your day

August 16, 2025

The secrets of the skin rejuvenation clinical for shiny skin

August 16, 2025

Crispy Basa Fish Pakoras (Fritters)

August 15, 2025
Facebook X (Twitter) Instagram
  • About Us
  • Contact Us
  • Privacy Policy
  • Terms and Conditions
  • Disclaimer
Facebook X (Twitter) Instagram
Healthtost
SUBSCRIBE
  • News

    How to move to a city can add 1,100 steps to your day

    August 16, 2025

    Consumption of over 60g of almonds a day can protect DNA and cut the oxidative damage

    August 15, 2025

    Respiratory viruses awaken inert breast cancer cells and increase the risk of relapse

    August 15, 2025

    Scientists decode internal speech from high -precision brain activity

    August 14, 2025

    PSMA PET/CT improves results for men with repetitive prostate cancer

    August 14, 2025
  • Mental Health

    Frustrated by all the bad news? Here is how to stay up -to -date but still take care of yourself

    August 15, 2025

    Transitions to school can cause stress and anxiety-these 5 books can help

    August 10, 2025

    National Month of Readiness: Design for Destruction and Emergency Situations

    August 6, 2025

    How do you feel about taking exams? Our research exceeded 4 types of test testers

    August 5, 2025

    Action is the antidote to ecological sadness and climate anxiety – explains an ecology

    July 31, 2025
  • Men’s Health

    5 days Dumbbell Workout split to build strength and muscles

    August 14, 2025

    Lavender oil could accelerate recovery after surgery on the brain

    August 12, 2025

    Stroke now clearly pulls in 205 and counting

    August 12, 2025

    Do you work with pain? You’re not alone.

    August 11, 2025

    How to divorce-from-backs your marriage: the simple secret your wedding advisor won’t tell you

    August 11, 2025
  • Women’s Health

    Lunch preparation for children and reduction of packed snacks

    August 15, 2025

    When choosing their own snacks: How to guide adolescents to healthy habits (without drama)

    August 12, 2025

    How long have you been leaving a dilator? A guide to safe and effective – Vuvatech

    August 10, 2025

    Irina Haller: In horses, high fashion and building a life moving on purpose

    August 9, 2025

    Practical gift ideas for women in menopause

    August 8, 2025
  • Skin Care

    The secrets of the skin rejuvenation clinical for shiny skin

    August 16, 2025

    A targeted way of dealing with Cellulite-Skincare doctors

    August 15, 2025

    Your final guide to facial oxygen Joanna Vargas

    August 14, 2025

    The hidden causes of compromised skin (for which no one speaks)

    August 14, 2025

    All for your sunlight and skin

    August 13, 2025
  • Sexual Health

    Enjoying intimacy despite sexual pain and hassle

    August 14, 2025

    $ 150 billion to release immigrants? Here are 4 other ideas.

    August 11, 2025

    The artist behind the cover

    August 11, 2025

    Is the semen of swallowing good for you?

    August 10, 2025

    Aasect Certified Sex Therapist Amanda Jepson Talks Kink – Sexual Health Alliance

    August 9, 2025
  • Pregnancy

    Why doctors recommend folic acid before and during pregnancy

    August 11, 2025

    Alternative treatments and repellent mosquito mosquitoes

    August 11, 2025

    Safe places for birth disappear in rural America – what should mothers know

    August 10, 2025

    5 wellness myths that sabotage pregnancy and postpartum journey

    August 9, 2025

    Things to do in a Playdate that will not leave you Frazzled

    August 8, 2025
  • Nutrition

    Crispy Basa Fish Pakoras (Fritters)

    August 15, 2025

    Caviar of Mississippi – Sharon Palmer, The Plant Powered Dietitian

    August 15, 2025

    Health Tips for Healthy Hair: Reviewing Slicked-Back “Do”

    August 13, 2025

    How to start organizing a dirty house • Kath eats

    August 12, 2025

    Are carboxymethythyyl cellulose, polysorbate 80 and other emulsifiers?

    August 11, 2025
  • Fitness

    Social connection and mental health

    August 15, 2025

    World Heart Day – Nutrition Tips for a Healthy Heart

    August 15, 2025

    How should you eat when your diet is over?

    August 14, 2025

    Strength Education 101: Proven Authorities, Elevators and Training Programs to build real power

    August 14, 2025

    25 minutes speed train de Joel Freeman

    August 13, 2025
Healthtost
Home»News»Increased milk intake associated with reduced risk of type 2 diabetes in non-lactase producing adults
News

Increased milk intake associated with reduced risk of type 2 diabetes in non-lactase producing adults

healthtostBy healthtostJanuary 22, 2024No Comments5 Mins Read
Facebook Twitter Pinterest LinkedIn Tumblr Reddit WhatsApp Email
Increased Milk Intake Associated With Reduced Risk Of Type 2
Share
Facebook Twitter LinkedIn Pinterest WhatsApp Email

Researchers of a recent study published in Metabolism of Nature investigated the relationship between milk consumption and type 2 diabetes (T2D) among non-lactase-intolerant individuals (LNP).

Study: A variant of the lactase gene LCT explains the link between milk intake and type 2 diabetes. Image credit: Yurii_Yarema/Shutterstock.com

Record

Cow’s milk is part of the human diet. However, its relationship with T2D is debatable. The effects of milk and dairy products on T2D risk are unclear and vary by population. Recent research reveals a link between the lactase gene (LCT), milk consumption and gut microbiota, with a genome-wide association study (GWAS) linking the host LCT locus to oligosaccharide/lactose-absorbing Bifidobacterium species milk and can be used as probiotics to reduce inflammation.

About the study

In the present study, researchers investigated whether consuming more milk reduces the risk of T2D in LNPs but not LPs by altering gut microbiota composition and circulating metabolites, potentially affecting host metabolic health.

The team conducted a GWAS of daily milk intake among 12,653 participants in the Hispanic Community Study/Study of Latinos (HCHS/SOL), identifying single nucleotide polymorphisms (SNPs) associated with milk intake. They calculated dietary intake using the National Cancer Institute (NCI) technique and quantified dairy intake in daily servings, divided into categories of milk, cheese, and yogurt.

The group genotyped blood-derived deoxyribonucleic acid (DNA) and analyzed serum metabolomics in 3,972 randomized patients who provided reference samples. Correlation analyzes included 624 known metabolites from more than 80% of subjects at baseline. They performed metagenomic sequencing on stool DNA obtained from 3,035 HCHS/SOL participants during follow-up.

The team used linear mixed-effects regression models to analyze milk intake among 12,653 subjects, controlling for field center, age, sex, first five principal components of genetic variation and sample weight. They divided participants into LCT-rs4988235 GG (LNP group) and LCT-rs4988235 AA/AG (LP group). They used multivariate Poisson regression models to investigate the relationships between daily consumption of milk, cheese and yogurt and the occurrence of T2D, stratified by LCT gene.

In addition, the team prospectively evaluated associations between metabolites associated with LCT genotype and T2D risk and their potential mediating effects on the relationship between milk intake and risk. Furthermore, they replicated the LCT-milk consumption interaction on T2D risk and the associations between circulating metabolites and T2D risk in the UK Biobank (UKBB) and Atherosclerosis Risk in Communities (ARIC) studies.

Results

The study showed that increased milk intake was associated with a reduced risk of T2D in people with LNP [relative risk (RR), 0.7] but not in lactase persisters (RR,1.2), controlling for demographic, socioeconomic, and behavioral characteristics. There were no associations with LCT genotype for cheese or yogurt consumption in the UKBB. Meta-analysis in nonwhite groups yielded comparable results (RR, 0.8). In contrast, a meta-analysis of 18 studies including mostly non-Hispanic white subjects with a high incidence of lactose intolerance revealed a slight positive association between milk consumption and T2D risk (RR, 1.0).

The Alternative Health Diet Index 2010 (AHEI 2010), which assesses diet quality, showed minimal relationships between diet components and milk intake, with comparable patterns between lactose-intolerant and lactose-intolerant adults. Further changes in AHEI-2010 or dietary components did not affect LCT-milk interactions on T2D risk or associations between milk consumption and diabetes-related metabolic characteristics.

The Analysis of Microbiome Composition (ANCOM) II survey revealed six and 13 factors associated with milk consumption in LP and LNP subjects, respectively. Seven species of Bifidobacterium and B. fragilis showed positive associations with milk consumption among LNP subjects. In contrast, five bacterial species, including Roseburia faecis, Bilophila wadsworthia and Prevotella, were associated with lower milk consumption. The team found positive associations between species within a genus and inverse associations between the genera Bifidobacterium and Prevotella.

Species associated with milk among non-lactose-intolerant individuals were typically unassociated with those among lactose-intolerant individuals, with similar results observed when examining associations independent of LCT genotype groups. Using linear regressions controlling for the variables included in the ANCOM-II analysis showed that the relationships between identified bacterial species and milk consumption were LCT gene specific, with significant LCT-milk gene interactions detected for most identified species .

Among 624 metabolites, the study identified 62 and 79 metabolites associated with milk consumption in LNP and LP subjects, respectively. The milk-related metabolite score for GG was strongly associated with reduced risk of T2D and positively with profiles of several metabolic traits. However, Mendelian randomization (MR) estimates for the remaining nine metabolites were non-significant.

conclusion

Overall, the study findings indicated a protective association between milk consumption and T2D in Hispanic/Latino individuals, likely related to gut microbiota and blood metabolites. LCT genotype may influence this interaction, with a strong protective association observed exclusively among LNP subjects.

This study helps to better understand the impact of milk consumption on human metabolic health by examining host genetics, gut microbes and circulating metabolites. Additional studies, including experimental trials, may confirm these findings.

adults Diabetes increased intake Milk nonlactase producing reduced risk type
bhanuprakash.cg
healthtost
  • Website

Related Posts

How to move to a city can add 1,100 steps to your day

August 16, 2025

Consumption of over 60g of almonds a day can protect DNA and cut the oxidative damage

August 15, 2025

Respiratory viruses awaken inert breast cancer cells and increase the risk of relapse

August 15, 2025

Leave A Reply Cancel Reply

Don't Miss
News

How to move to a city can add 1,100 steps to your day

By healthtostAugust 16, 20250

A national study shows that relocation to a more wandering city leads to continuous increases…

The secrets of the skin rejuvenation clinical for shiny skin

August 16, 2025

Crispy Basa Fish Pakoras (Fritters)

August 15, 2025

Social connection and mental health

August 15, 2025
Stay In Touch
  • Facebook
  • Twitter
  • Pinterest
  • Instagram
  • YouTube
  • Vimeo
TAGS
Baby benefits body brain cancer care Day Diet disease exercise finds Fitness food Guide health healthy heart Improve Life Loss Men mental Natural Nutrition Patients Pregnancy protein research reveals risk routine sex sexual Skin study Therapy Tips Top Training Treatment Understanding ways weight women Workout
About Us
About Us

Welcome to HealthTost, your trusted source for breaking health news, expert insights, and wellness inspiration. At HealthTost, we are committed to delivering accurate, timely, and empowering information to help you make informed decisions about your health and well-being.

Latest Articles

How to move to a city can add 1,100 steps to your day

August 16, 2025

The secrets of the skin rejuvenation clinical for shiny skin

August 16, 2025

Crispy Basa Fish Pakoras (Fritters)

August 15, 2025
New Comments
    Facebook X (Twitter) Instagram Pinterest
    • About Us
    • Contact Us
    • Privacy Policy
    • Terms and Conditions
    • Disclaimer
    © 2025 HealthTost. All Rights Reserved.

    Type above and press Enter to search. Press Esc to cancel.