Author: healthtost

Researchers at the University of Wisconsin-Madison have identified a protein key to the development of a type of brain cell believed to play a role in disorders such as Alzheimer’s and Parkinson’s diseases, and used the discovery to grow neurons from stem cells for the first time. Stem cell-derived norepinephrine neurons of the type found in a part of the human brain called the locus coeruleus could enable research into many psychiatric and neurodegenerative diseases and provide a tool for developing new ways to treat them. Yunlong Tao, a researcher at Nanjing University in China who was a research professor…

Small molecules called immunomodulators can help create more effective vaccines and stronger immunotherapies to treat cancer. But finding the molecules that trigger the right immune response is difficult – the number of drug-like small molecules has been estimated at 1060much higher than the number of stars in the visible universe. In a possible first for the field of vaccine design, machine learning guided the discovery of new molecules that enhance the immune pathway and found a specific small molecule that could outperform the best immunomodulators on the market. The results are published in the journal Chemical Science. “We used artificial…