Close Menu
Healthtost
  • News
  • Mental Health
  • Men’s Health
  • Women’s Health
  • Skin Care
  • Sexual Health
  • Pregnancy
  • Nutrition
  • Fitness
What's Hot

Long -term exposure to air pollution associated with early signs of heart damage

July 1, 2025

Kettlebell Deadlifts Ultimate Guide for the form of strength and power

July 1, 2025

Life after Hellp Syndrome – Hygiene

July 1, 2025
Facebook X (Twitter) Instagram
  • About Us
  • Contact Us
  • Privacy Policy
  • Terms and Conditions
  • Disclaimer
Facebook X (Twitter) Instagram
Healthtost
SUBSCRIBE
  • News

    Long -term exposure to air pollution associated with early signs of heart damage

    July 1, 2025

    Rarely studied RNA associated with triple negative breast cancer

    July 1, 2025

    Who certifies Surinam as free malaria after decades of attempts

    June 30, 2025

    The new AI tool helps clinical doctors identify standards of brain activity associated with nine types of dementia

    June 30, 2025

    Organ chip technology accurately predicts chemotherapy response to patients with esophageal adenocarcinoma

    June 29, 2025
  • Mental Health

    Does psychiatric drug kill creativity? Rejecting Van Gogh’s myth

    June 30, 2025

    Which one is right for you? – Talkspace

    June 27, 2025

    Do alternative treatments for bipolar disorder work? Guide based on evidence (2025)

    June 26, 2025

    Data reveals both challenges and positive trends

    June 16, 2025

    How to choose the best yoga teacher training in Rishikesh

    June 14, 2025
  • Men’s Health

    Kettlebell Deadlifts Ultimate Guide for the form of strength and power

    July 1, 2025

    The Role of Phytandrogens in BPH

    June 30, 2025

    Just 150 minutes of exercise per week could prediabetes reversed

    June 30, 2025

    How Barefoot Workout can make you stronger, more athletic and stunning in injuries

    June 29, 2025

    How I turned the chatgpt to my personal nutrition coach and you can also

    June 29, 2025
  • Women’s Health

    Life after Hellp Syndrome – Hygiene

    July 1, 2025

    Top Home workouts for women 10 exercises to lose belly fat quickly

    June 30, 2025

    Books I have recently read – The Fitnessista

    June 29, 2025

    Does it support your aesthetic travel your body and mind? Guide

    June 28, 2025

    Eating for real immune support this winter

    June 27, 2025
  • Skin Care

    Aging with grace how menopause can cause changes in the skin

    July 1, 2025

    Term Science: Why these tiny bottles are loud

    June 30, 2025

    Sunburn First Aid -7 common mistakes you will regret later

    June 29, 2025

    What is happening first? The step by step guide to build a routine of skin care

    June 28, 2025

    DIY Vitamin C Cucumber The Eye Serum

    June 27, 2025
  • Sexual Health

    What kind of professional community is most important to you? Exploring the benefits of SHA’s sex network – Alliance of Sexual Health

    June 30, 2025

    Can Koles really get chlamydia?

    June 28, 2025

    Overward Visitor and Student Health Insurance in Australia for visa holders

    June 27, 2025

    Disassociation of the latest testosterone treatment lines

    June 27, 2025

    We always know that orgasms were good for you. Now there is proof.

    June 26, 2025
  • Pregnancy

    Naturally support your baby’s health

    July 1, 2025

    New Pink Magnesium Glucker, L-thean

    July 1, 2025

    AI helps the couple capture after 19 years and 15 IVF attempts

    June 29, 2025

    7 signs your gut can be out of balance

    June 29, 2025

    Helping parents prepare for birth with calm and trust

    June 28, 2025
  • Nutrition

    15 minutes Korean beef tacos (family friendly + one Pan!)

    July 1, 2025

    25 best vegan taco recipes that are healthy, easy and full of flavor

    June 29, 2025

    Episode 004: Trust your truth against all logic with Angela de la Agua

    June 28, 2025

    Benefits for the health of CoQ10 you should be aware

    June 27, 2025

    Creatine Completion in Menopause: What does science say?

    June 27, 2025
  • Fitness

    The success story of the AFPA Students – Dr. Nikki Letoya White

    June 30, 2025

    15 easy ways to get 20 grams of protein (Personal Trainer Guide)

    June 29, 2025

    Review of the Heat Index: an approach based on evidence

    June 28, 2025

    Bodybuilding Legend Charles Glass’ 5 Favorite Movements Hamstring

    June 27, 2025

    7 Best energy gels 2025, per runners and dieticians

    June 26, 2025
Healthtost
Home»News»Alarming spread of H5N1 avian flu in US dairy cattle reveals risks of cross-species transmission
News

Alarming spread of H5N1 avian flu in US dairy cattle reveals risks of cross-species transmission

healthtostBy healthtostJuly 26, 2024No Comments6 Mins Read
Facebook Twitter Pinterest LinkedIn Tumblr Reddit WhatsApp Email
Alarming Spread Of H5n1 Avian Flu In Us Dairy Cattle
Share
Facebook Twitter LinkedIn Pinterest WhatsApp Email

In a recent study published in the journal Nature, scientists in the United States report the spread of highly pathogenic avian influenza (HPAI) H5N1 virus in cattle in various regions of the United States (US). They further document the detailed symptomatic effects of the resulting disease in these cattle populations. Finally, they use a multidisciplinary approach incorporating epidemiological and genomic analyzes to highlight that virus evolution provides the potential not only to allow cow-to-cow transmission but also efficient multidirectional spread between species, infecting birds, domestic cats, and even and a raccoon. proximity to sick cattle.

Study: Dissemination of H5N1 highly pathogenic avian influenza virus in dairy cattle. Image credit: Studio Romantic / Shutterstock

Record

Influenza A virus (IAV) H5Nx is a highly pathogenic avian influenza (HPAI) virus that causes widespread respiratory disease and subsequent death in avian populations throughout Africa, Asia, Europe and more recently North America. First discovered in China in 1996, the colloquial “bird flu” has since evolved into eight clades and three neuraminidase subtypes, with the H5N1 2.3.4.4b subtype being its most widespread and epidemiologically relevant agent.

HPAI H5N1 is of concern given the potential for spillover (cross-species infectivity). It has been reported to be transmitted from infected poultry populations to wild birds (2002), mammals (domesticated and wild), and even humans (2003). The World Health Organization (WHO) has recorded 860 human infections and more than 430 deaths since 2003 (mortality rate ~52.8%).

The virus poses significant ecological, economic, and public health threats, having killed more than 90 million birds in the United States (US) alone. The most recent morbidity event associated with H5N1 was in dairy cattle in Texas (TX), New Mexico (NM), Kansas (KS), and Ohio (OH) between January and March 2024. Understanding Epidemiologic and Genomic substrates of this event may allow researchers to elucidate the etiology (origin) of the disease and prepare for future outbreaks.

Influenza A (H5N1/Bird Flu) Influenza A (H5N1/Bird Flu) virus particles (round and rod-shaped, red and yellow).  Creative composition and coloring/effects by NIAID.  Transmission electron micrograph images courtesy of CDC.  Scale modified/not to scale.  Credit: CDC and NIAID

Influenza A (H5N1/Bird Flu) Influenza A (H5N1/Bird Flu) virus particles (round and rod-shaped, red and yellow). Creative composition and coloring/effects by NIAID. Transmission electron micrograph images courtesy of CDC. Scale modified/not to scale. Credit: CDC and NIAID

About the study

This study documents the incidence of morbidity from January to March 2024 in US cattle across TX and its neighboring states. It uses a detailed interdisciplinary approach that integrates clinical, epidemiologic, and phylogenetic investigations to elucidate the pathophysiology of the virus and the genetic underpinnings of viral dispersibility.

The researchers initially obtained samples for the clinical-epidemiologic evaluation from nine farms in the affected states – TX (5 farms), NM (2), KS (1), and OH (1). Specifically, the only farm in OH was affected after cattle (assumed to be healthy) were imported from the first affected TX farm.

Data collection included nasal swabs, milk, dialysis pads, and serum (n = 331). These samples were subjected to real-time reverse transcriptase polymerase chain reaction (rRT-PCR) and viral metagenomic sequencing. In addition, tissue from birds (big-tailed, rock pigeons) and mammals (cats and raccoons) found dead on contaminated farms were subjected to rRT-PCR analysis.

Virus shedding studies were conducted to elucidate the source and duration of virus transmission after initial infections. The excised tissues from cows, dead birds and mammals were subjected to histological examinations. Finally, phylogenetic analyzes were performed to isolate the causative source of the viral strain and the genetic underpinnings of its significant spread.

Study findings

Clinical-epidemiological investigations revealed multiple disease symptoms in cattle, mainly reduced feed intake, mild respiratory distress, reduced rumination time, lethargy, dehydration, abnormal faeces and abnormal milk production (20-100% reduction in quantity, yellow color and thick consistency ). Symptoms persisted for 5-14 days. However, milk production remained reduced for up to four weeks.

All investigated rRT-PCR samples detected positive viral load, but viral shedding was the highest and most frequently detected in milk and mammary gland tissue samples. Specifically, while virus shedding studies detected viral loads in milk samples on days 3, 16, and 31 post-infection, shedding of infectious virus was observed only on day 3.

“Histological examination of tissues from affected dairy cows revealed marked changes consisting of neutrophilic and lymphoplasmacytic mastitis with apparent obliteration of the tubular gland architecture that was filled with neutrophils admixed with cellular debris in multiple lobules in the mammary gland. The most pronounced changes in his cat The tissues consisted of mild to moderate multifocal lymphohistiocytic meningoencephalitis with multifocal areas of parenchymal and neuronal necrosis.’

Phylogenomic analysis revealed that all recovered viral sequences align with a new monophyletic H5N1 reassortant subtype called B3.13, which was first discovered in a Canada goose in Wyoming (January 25, 2024). This lineage was most closely related to a sequence obtained from a dead skunk in NM (23 Feb 2024). The similarity between the viral genomes from the examined farms highlights circulation and cross-contamination between their inhabitants, possibly due to the transfer and introduction of animals between these farms.

conclusions

The present study highlights the potential for H5N1 virus spillover and cross-infection in avian and mammalian hosts on US farms. The mammary gland was identified as the site of highest viral replication, with contaminated milk representing the most likely route of transmission. The new substrate (B3.13) identified here is of concern given the potential for spread (in domestic and wild bird populations, and even other mammals – cats and raccoons).

Although no human infections were reported from non-study farms, mild infections were reported during the study from other farms near the study area, highlighting the zoonotic potential of the virus and the possibility of a human pandemic.

Protective measures

According guidelines from the CDC, it is important to wear recommended personal protective equipment (PPE) when working directly or closely with sick or dead animals, such as animal feces, litter, raw milk, and other materials that may have the virus. Recommended PPE includes liquid-resistant coveralls, waterproof apron, NIOSH-approved respirator (eg, N95), properly fitted non-vented or indirectly ventilated safety glasses or face shield, head or hair cover, gloves, and boots.

Proper procedures for putting on and removing PPE, such as washing hands before and after using PPE and disinfecting reusable PPE after each use, are essential. In addition, it is recommended that you shower at the end of the work shift, leave all contaminated clothing and equipment at work, and monitor for symptoms of illness for ten days after working with potentially sick animals or materials.

alarming avian Cattle crossspecies dairy Flu H5N1 reveals Risks spread transmission
bhanuprakash.cg
healthtost
  • Website

Related Posts

Long -term exposure to air pollution associated with early signs of heart damage

July 1, 2025

Rarely studied RNA associated with triple negative breast cancer

July 1, 2025

Who certifies Surinam as free malaria after decades of attempts

June 30, 2025

Leave A Reply Cancel Reply

Don't Miss
News

Long -term exposure to air pollution associated with early signs of heart damage

By healthtostJuly 1, 20250

Researchers using cardiac magnetic resonance imaging have found that long -term exposure to air pollution…

Kettlebell Deadlifts Ultimate Guide for the form of strength and power

July 1, 2025

Life after Hellp Syndrome – Hygiene

July 1, 2025

Naturally support your baby’s health

July 1, 2025
Stay In Touch
  • Facebook
  • Twitter
  • Pinterest
  • Instagram
  • YouTube
  • Vimeo
TAGS
Baby benefits body brain cancer care Day Diet disease exercise finds Fitness food Guide health healthy heart Life Loss Men mental Natural Nutrition Patients Pregnancy protein research reveals Review risk routine sex sexual Skin study Therapy Tips Top Training Treatment Understanding ways weight women Workout
About Us
About Us

Welcome to HealthTost, your trusted source for breaking health news, expert insights, and wellness inspiration. At HealthTost, we are committed to delivering accurate, timely, and empowering information to help you make informed decisions about your health and well-being.

Latest Articles

Long -term exposure to air pollution associated with early signs of heart damage

July 1, 2025

Kettlebell Deadlifts Ultimate Guide for the form of strength and power

July 1, 2025

Life after Hellp Syndrome – Hygiene

July 1, 2025
New Comments
    Facebook X (Twitter) Instagram Pinterest
    • About Us
    • Contact Us
    • Privacy Policy
    • Terms and Conditions
    • Disclaimer
    © 2025 HealthTost. All Rights Reserved.

    Type above and press Enter to search. Press Esc to cancel.