People with underwater thyroid may have an increased risk of developing a small intestine of bacterial over -development (SIBO), a risk that may be reduced by the treatment of thyroid hormones, according to a study presented on Saturday at Endo 2025, the annual meeting of the endocrine.
We now know that people with hypothyroidism, especially those with autoimmune thyroiditis, are more likely to develop SIBO, but this risk seems to be mitigated by those who take thyroid drugs. ”
Ruchi Mathur, MD, Director of the Diabetes Outpataties Center for Healing and Education and Director of Medically Connected Science and Technology Clinics at Cedars-Sinai in Los Angeles, California.
Mathur said their research also suggests that there could be a microbiological mechanism that leads this union, which could lead to more personalized treatments.
Researchers investigated the relationship between Sibo and hypothyroidism in people over the age of 18 who previously underwent an upper endoscopy without preparing the colon and reported that they lived with hypothyroidism as well as tests. The subjects were hired through the flagship of the Reimagine study.
Small intestinal fluid samples were analyzed by 49 people with hypothyroidism and 323 without the condition and performed DNA sequence to detect microbial species. The results showed that people with hypothyroidism had a significantly higher prevalence of SIBO than witnesses (33% vs. 15%).
Mathur and her colleagues further evaluated four groups: Sibo-positive with hypothyroidism, sibo-negative with hypothyroidism, sibo-visual thyroid illness and sibo-negative without thyroid disease.
The analysis showed different patterns of bacteria in the intestine depending on a person’s thyroid condition and the coexistence of Sibo.
Separately, they carried out a large -scale medical records from the TRINETX database, which examined the 10 -year Sibo development risks in people with hypothyroidism or autoimmune thyroiditis compared to their respective witnesses. The risks were also mitigated in people receiving levothyroxine.
“The results have shown that the risk of developing SIBO in people with hypothyroidism is 2.2 times more than the risk of a corresponding control group and was 2.4 times higher in those with autoimmune thyroiditis compared to the group presented by the Margine program, MDI, MD, MD, ENGARET FEELEEDSHYS.
“These findings open the door to new promotion and prevention strategies, for example, doctors may begin monitoring thyroid health in sibo patients and vice versa, it also supports the idea that improved bowel health could have extensive effects, Hashimoto, “Mathur, he said. “As the research goes on, this could lead to more personalized care and previous interventions for people at risk.”
