A 1 -star Customer Review recently came to what my eye fell. Joe wrote:
“Don’t take Cistanche! I read online that Cistanche inhibits the production of nitric oxide.
Strong words. I’m not sure where he gets his information but he is full inaccuracies and imperfection. Let me give you more complete picture.
Let’s start with “Nitrate Oxide is key No. 1 to treat ed”…
Nitrate oxide is very important… but not treatment-all. It really depends on what it is causing ED First.

- More nitric oxide will do nothing for those suffering from erectile dysfunction caused by porn. (Ask me how I learned it!)
- More nitrate oxide will do nothing for someone who has nerves cut off from prostate surgery
- More nitric oxide will do nothing for someone whose ED comes from SSRI.
- More nitric oxide could be useful for a heavy smoker, but what will work better than it is to pour smoking and seek to restore tissues, not only to reinforce no.
I would say the key number one to determine ED Determination of what causes it First. Once you have this, you can see if the nitric oxide or something should be done.
Now let’s move on to nitric oxide especially. While playing a vital role in blood flow, it is important for the health and gender of the heart can lead to problems.
This is correct, as almost everything in the body, nitrate oxide (no) is all balance.
- Excessive not in the brain can lead neurotoxicity-It means that it can damage brain cells and lead to neurodegenerative diseases.
- Since it does not help expand blood vessels, too much can cause dangerous low blood pressure (hypotension), leading to dizziness, fainting and fatigue.
- NO is used by the cells of the immune system to kill pathogens, but too much can Inflammation of fuel and tissue damage.
- Is particularly problematic autoimmune diseases or chronic infections where the immune system is already excessive.
- High NO can interact with other molecules formAn extremely reactive union that causes oxidative stress, which destroys proteins, DNA and cell membranes.
- No can be done root freewhich accelerates aging and contributes to chronic illness.
That everything could scare you from no but usually people could use more of his, no less.
I share all this to say that the very preliminary evidence shows that Cistanche can shape no one instead of a single direction. Ah, we have the intelligence of herbs to work here …
Such a study shows That Echunakoside (ECH), one of the main compounds found in Cistanche, helps your blood vessels produce more nitric oxide by activating an essential enzyme, ENOS (endothelial nitrate oxide). This effect occurs through a natural chain reaction to your cells that also include testosterone -related paths.
But still, maybe Joe came into something I missed, so I dug further.
This criticism lists a variety of studies showing both increases and reductions, such as “Suspension of activation of macrophages and nitric oxide production. Clean free radicals” and “Expressing the synthesis of nitrogen nitric oxide” and “pure non -radical”.
What do these studies have in common? Antioxidant effects and the immune system were examined.
In addition, almost everything here was cellular studies, A long scream From its effects in life, breathing people.
According to the ancient Chinese, Cistanche directs blood flow to the genital area. That is why this herb was used 80% of the types of sexual power Back to the day. I will trust it in cellular studies any day of the week. (And there are some human trials of Cistanche and various sexual studies available from way.)
So while joke experiences like Joe’s are valid on this Not every herb works for everyoneThe underlying claim – that Cistanche inhibits nitrate oxide-It’s not true.
Just to show you this is the case, let’s take a look at the star of Joe’s criticism, Horny Goat Weed.
The main union in Horny Coat Weed (also known as Epimedium), called Icariin, helps improve blood flow, enhancing not in a few clever ways:
- Endothelial Nitric Oxide (ENOS) activity
- Increasing the Tetradro -Sodium (BH4), which prevents ENOS disconnection and maintains the composition No.
- Suspension PDE5
But what else do we see? Much the same thing some two -way activity without no.
Horny Goat Weed also goes in the other direction. Can Reduce inflammation By blocking the signals that say in your immune system to go to overdrive and do too much.
By activating the antioxidant trails, this compensates for oxidative stress caused by overproductionwhich can contribute to DNA damage and cellular aging.
The same kind of functions we saw with Cistanche. This two -way activity is one of the benefits of herbs over isolated drugs that tend to drive one thing in one direction only.
There is one reason that Thor’s Hamm’s formula contains both Cistanche and Horny Coat Weed as well as some other powerful herbs.
Now, the one thing I will say that Joe is not wrong is that he said that Cistanche was not working for him. While it cannot be a specialist in science or biology, He is a specialist to himself.
That’s why we have our own One -year money guarantee. But please do not throw herbs into the trash. Give them to someone else at least then contact us to receive your refund or exchange.
I hope you have found this exploration of the deeper causes of ED, good and bad nitrogen oxide and dual -direction activity of the weed goat and cistanche lighting.
Reports:
1. The nitrogen -induced by echinakoside in endothelial cells: androgen receptor roles and R3K -akt road. International Journal of Molecular Medicine, 45, 1195-1202. https://doi.org/10.3892/ijmm.2020.4476
2. Wang, N., Ji, S., Zhang, H., Mei, S., Qiao, L., & Jin, H. (2017). Herba Cistanches: anti-aging. Aging and illness, 8 (6), 740-759. https://doi.org/10.14336/ad.2017.0720
3. Cui, J., Lin, L., Hao, F., Shi, Z., Gao, Y., Yang, T., Yang, C., Wu, X, Gao, R., Ru, Y, Li, F., Xiao, C., Gao, Y, & Wang, Y. (2024). Comprehensive review of traditional uses and potential benefits of epimedium folium. Frontiers in Pharmacology, 15, 1415265. https://doi.org/10.3389/fphar.2024.1415265