The incidence of heart attacks and strokes was lower after the COVID-19 vaccination than before or without vaccination, according to a new study involving almost the entire adult population of England.
The study, published today in Nature communicationsIt showed that the incidence of arterial thrombosis, such as heart attacks and strokes, was up to 10% lower at 13 to 24 weeks after the first dose of a Covid-19 vaccine. After a second dose, the incidence was up to 27% lower after the Astrazeneca vaccine was taken and up to 20% lower after the Pfizer/Biotech vaccine.
The incidence of common venous thrombosis – mainly pulmonary embolism and deep venous thrombosis of the lower extremity – was followed by a similar pattern.
The research led by the universities of Cambridge, Bristol and Edinburgh and Edinburgh and the British Heart Science Center (BHF) in Health Data Research UK analyzed the disabled health from 46 million adults in England between December 8 and 2020.
The co-author Dr Samantha IP, a researcher at the Department of Public Health and Primary Care, University of Cambridge, said: “We studied Covid-19 vaccines and cardiovascular disease in nearly 46 million adults in England and found a similar or lower incidence of common cardiovascular disease, such as heart attacks and strokes, after each vaccine.“
Previous studies have found that the incidence of rare cardiovascular complications is higher after certain COVID-19 vaccines. For example, the incidence of myocarditis and pericarditis has been reported after mRNA -based vaccines such as the Pfizer/Biotech vaccine and thrombocytopenia thrombocytopenia -caused vaccine -based vaccine -based vaccine. This study supports these findings, but mainly does not detect new adverse cardiovascular conditions associated with COVID-19 vaccination and offers further assurance that the benefits of vaccination exceed the risk.
The incidence of cardiovascular disease is higher after Covid-19, especially in severe cases. This can explain why the incidence of heart attacks and strokes is lower in vaccinated people compared to non -vaccinated people, but further explanations are beyond the scope of this study.
The COVID-19 vaccination program began strongly in the United Kingdom, with over 90% of the population over 12 years of age vaccinated with at least one dose until January 2022.
This study throughout England offers patients the assurance of cardiovascular safety of first, second and reinforcement doses of COVID-19 vaccines. It shows that the benefits of the second and souvenir doses, with fewer common cardiovascular events, include heart attacks and stroke after vaccination, compensate for very rare cardiovascular complications. “
Professor William Whiteley, Deputy Director at the BHF Data Science Center and Professor of Neurology and Epidemiology at the University of Edinburgh
The research team used the connected data identified by GP practices, hospital admissions and death records analyzed in a secure data environment provided by NHS England.
The editor of co-ending Dr Venexia Walker, a researcher at the University of Bristol, said: “Given the critical role of COVID-19 vaccines in the protection of people from COVID-19, it is important to continue to study the benefits and dangers associated with them. Data availability throughout the population has allowed us to study different combinations of COVID-19 vaccines and consider rare cardiovascular complications. This would not be possible without the very big data we are privileged in our access and close partnerships.“
Source:
Magazine report:
Ip, S., et al. (2024). Corte study of Cardiovascular Security of different doses of COVID-19 vaccination -9 between 46 million adults in England. Nature communications. Doi.org/10.1038/S41467-024-49634-X.
