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Scientific Review of “Liquid Mi – OUMERE

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</p><p> The Biological Hazard of Spicules: A Scientific Critique of “Liquid Mi – OUMERE</p><p>


















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The Biological Hazard of Spicules: A Scientific Critique of “Liquid Microneedling”

February 04, 2026By Wendy Ouriel

UMERE

Summary

The skin care industry has recently popularized “spicules” — tiny needle-like structures derived from sea sponges — as a non-invasive alternative to microneedling. While marketed as a revolutionary delivery system, the mechanical action of the spicules involves the deliberate, sustained puncturing of the stratum corneum. This article reviews the physiological consequences of such trauma, including the induction of chronic subclinical inflammation and the compromise of selective skin permeability.

1. The Anatomy of a Breach: Mechanical Trauma at the Micro-Scale

Spicules (usually from Spongilla lacustris) are sharp, siliceous or calcareous fragments. Unlike professional microneedling, which involves controlled, vertical punctures that are immediately withdrawn, the spicules are massaged into the skin and remain fixed for 48 to 72 hours [1].

  • The depth of the attack: Coils usually penetrate 0.1 to 0.3 mm into the skin, reaching the living layers of the epidermis.
  • The foreign body response: Because the skin cannot “digest” the silica fragments, it activates an immune response to eliminate them. This is the source of the “stingy” sensation that users feel – it’s not “activation”, it’s an acute inflammatory reaction to a foreign invader [2].

2. The “enhanced absorption” fallacy

The main marketing claim for the spicules is that they increase the absorption of ingredients by up to 3,000%. However, from a biological point of view, this “benefit” is a disastrous liability.

Indiscernible Permeability: The micro-channels created by the spicules do not distinguish between “pure” active and environmental toxins. When you break the barrier, you allow particulate matter (PM2.5), heavy metals and pathogenic bacteria to have direct access to the dermis [10].

Additionally, ingredients such as phenoxyethanol, some surfactants and synthetic fragrances are safe on the surface, but become cytotoxic (cell killing) when forced into the deeper, living tissue [5].

3. “Inflammatory” and Long-Term Tissue Degradation

The most important risk of using spicule is chronic low-grade inflammation.

MMP activation

The presence of spicules activates Matrix Metalloproteinases (MMPs)—enzymes responsible for breaking down damaged tissue. However, chronic activation causes premature degradation of these enzymes Type I collagen and elastinleading to sagging and “inflammation of the skin” [3].

Barrier depletion

Repeated use of spicules leads to a state of permanent transepidermal water loss (TEWL). The skin becomes “addicted” to the temporary density of inflammation, while the underlying structure becomes increasingly dehydrated and fragile [2].

Intellectual Skincare

At UMERE, we do not create based on trends or viral fashions. Our philosophy is based on the knowledge that the skin is a sophisticated organ that requires support, not overthrow. We avoid the hype because your skin’s health is a long-term investment.

Shop the collection

References & Scientific Bibliography

[1] Elias, PM (2005). Stratum corneum antigenicity and a contact dermatitis epidemic. Immunopathology Seminars27(2), 305-317. doi:10.1007/s00281-005-0004-3. (Fundamental study of the barrier as an active immune organ).

[2] Krutmann, J., et al. (2017). Exposure to skin aging. Journal of Dermatological Science85(3), 152-161. (Research detailing how environmental toxins penetrate breached barriers to accelerate aging).

[3] Fisher, GJ, et al. (2001). Mechanisms of Photoaging and Chronological Aging of the Skin. Archives of Dermatology137(11), 1459–1463. (Critical evidence of how mechanical and environmental stress triggers MMP-1 collagen degradation).

[4] Pappas, A. (2009). Epidermal lipids. Dermatology-Endocrinology1(2), 72–76. (Discussion of the role of the lipid barrier in preventing indiscriminate molecular crossing).

[5] UMERE Research Laboratory (2025). Internal White Paper: The cytotoxicity of subcutaneous delivery systems. (Analysis of the cellular response to the transport of non-biocompatible components).


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