Close Menu
Healthtost
  • News
  • Mental Health
  • Men’s Health
  • Women’s Health
  • Skin Care
  • Sexual Health
  • Pregnancy
  • Nutrition
  • Fitness
What's Hot

30 minutes Kettlebell Core Workouts to strengthen your abdomen

June 9, 2025

Semaglutide for Weight Loss – Summer Safety and Side Effects Guide

June 9, 2025

Teenagers and sexual education during the Covid-19 pandemic and beyond

June 9, 2025
Facebook X (Twitter) Instagram
  • About Us
  • Contact Us
  • Privacy Policy
  • Terms and Conditions
  • Disclaimer
Facebook X (Twitter) Instagram
Healthtost
SUBSCRIBE
  • News

    AI model detects brain tumors with high precision using epigenetic fingerprints

    June 8, 2025

    The new study warns long -term risks from germ transplants

    June 8, 2025

    Self-collection tests could be a solution to increase access to cervical cancer control

    June 7, 2025

    Preeclampsia associated with long -term brave disbelief and worsening the effects of stroke

    June 7, 2025

    In Axing’s MRNA contract, Trump delivers another blow to US bio -security, former officials say

    June 6, 2025
  • Mental Health

    Heart attack or panic attack? Why do young people call ambulances for non -managed stress

    June 7, 2025

    My journey, my development, my truth – uninterrupted

    June 6, 2025

    Why I am fighting for mental health change

    June 3, 2025

    Girls with painful periods are twice as high as their peers to have symptoms of anxiety or depression

    June 2, 2025

    Does psychiatric drug kill creativity? Rejecting Van Gogh’s myth

    May 29, 2025
  • Men’s Health

    30 minutes Kettlebell Core Workouts to strengthen your abdomen

    June 9, 2025

    Scientists identify genetic indications that connect air pollution to neurodegeneration

    June 7, 2025

    Do you want a stronger back? This Powerlifter’s secret weapon is a secret weapon

    June 7, 2025

    Chains, bands and greater profits: Guide to deal with resistance

    June 6, 2025

    Phil Stutz, True Magic & Healing Mankind: Useful tools for today’s World – Part 2: Universe 1 and Universe 2

    June 6, 2025
  • Women’s Health

    Making the connection between collagen and recovery from exercise

    June 8, 2025

    Alice Connors for purpose and progress

    June 4, 2025

    8 teenagers of vitamins must actually get

    June 4, 2025

    Reasons for frequent urination

    June 3, 2025

    Life with myalgian encephalomyelitis/chronic fatigue syndrome

    June 3, 2025
  • Skin Care

    Semaglutide for Weight Loss – Summer Safety and Side Effects Guide

    June 9, 2025

    10 signs it’s time to see an acne expert

    June 8, 2025

    11 Important facts for Botox Botox hood

    June 7, 2025

    Liposcopy: Is it right for you?

    June 7, 2025

    Ideas for father’s day and beyond

    June 4, 2025
  • Sexual Health

    Teenagers and sexual education during the Covid-19 pandemic and beyond

    June 9, 2025

    The odd rise of cases of syphilis to heterosexual men in the UK

    June 8, 2025

    The Role of Certified LGBTQ Certified Sexual Therapist – Sexual Health Alliance

    June 7, 2025

    How Pride paved the way for sexual well -being

    June 5, 2025

    Best male masturbation positions Female

    June 4, 2025
  • Pregnancy

    Love in Melbourne Australia – Tiffany Rose Maternity Blog UK

    June 8, 2025

    How to remain calm with high blood pressure during pregnancy?

    June 7, 2025

    Pink Stork’s flagship product – as shown in “Empowered by Meg Ryan”

    June 7, 2025

    You don’t have to know everything – only that before birth

    June 6, 2025

    Top 100 Names of Girls 2024

    June 5, 2025
  • Nutrition

    The busy mom’s driver for intestinal-brain connection

    June 7, 2025

    Healthy Banana Bread (Child Approved) Sarah Remat

    June 6, 2025

    The secret to the loss of persistent belly fat by registered dieticians

    June 5, 2025

    Why are you always tired and what to do

    June 5, 2025

    20 herbal and wonderful recipes with appetizers

    June 4, 2025
  • Fitness

    Creamy all the toast Avocado bagel (easy, salty breakfast!)

    June 8, 2025

    Men’s Health Month: Dealing longevity vacuum

    June 7, 2025

    Best 12 biceps exercises ranked: build larger and stronger weapons

    June 6, 2025

    Próximamente el 10 de junio: 25 minutes of train de Joel Freeman

    June 5, 2025

    The best weight counter to add to your home gym in your 2025

    June 5, 2025
Healthtost
Home»News»Heat shock protein protects bacteria from plasma treatment
News

Heat shock protein protects bacteria from plasma treatment

healthtostBy healthtostNovember 26, 2023No Comments3 Mins Read
Facebook Twitter Pinterest LinkedIn Tumblr Reddit WhatsApp Email
Heat Shock Protein Protects Bacteria From Plasma Treatment
Share
Facebook Twitter LinkedIn Pinterest WhatsApp Email

A heat shock protein protects cells from protein aggregation. It degrades, however, over longer treatment periods.

Plasmas are used, for example, in wound treatment against pathogens that are resistant to antibiotics. However, bacteria can defend themselves: They use a heat shock protein that protects them. A research team led by Professor Julia Bandow and Dr. Tim Dirks from the Chair of Applied Microbiology at Ruhr University Bochum, Germany, showed that bacteria overproducing the heat shock protein Hsp33 can withstand plasma treatment more efficiently than others. The researchers also demonstrated which plasma components activate the heat shock protein. The team published their findings in the Journal of the Royal Society Interface on October 25, 2023.

All bacteria were inactivated after three minutes

When treated with plasma, proteins unfold, lose their natural functions and can clump together. Their accumulation is toxic to cells and can lead to their inactivation. The 33-kDa bacterial heat shock protein, referred to as Hsp33, prevents aggregation by binding unfolded proteins.

To find out whether excess Hsp33 protects cells from plasma, the researchers treated strains overproducing the protein with the plasma source Cinogy, which is already used in dermatology. These strains survived significantly better than wild-type bacteria after a short treatment of about one minute. “After a three-minute treatment, cells producing excess Hsp33 were also deactivated,” Tim Dirks points out.

Heat shock protein activating species

The researchers demonstrated that Hsp33 is activated by plasma by treating the purified heat shock protein with the plasma source. “This activation is related to the oxidation and unfolding of the protein and is actually reversible,” explains Tim Dirks. “However, we also showed that Hsp33 was completely degraded by longer plasma treatment times of one hour.” In addition, the ability of the protein to bind a zinc atom was negatively affected by plasma. This zinc atom reinforces the protein’s natural three-dimensional structure in its inactive state.

Since nothing was previously known about which plasma-produced species can activate Hsp33, the researchers created various stressors known to be produced in plasma and confronted Hsp33 with them one by one.

This showed that Hsp33 is activated by superoxide, singlet oxygen, and atomic oxygen, but is unresponsive to hydroxyl radicals and peroxynitrite.”


Tim Dirks, Chair of Applied Microbiology, Ruhr University Bochum, Germany

This gives an indication of the interaction of these species with bacterial cells. For example, superoxide is one of the first species created by oxidative stress in the body, such as by our immune system in macrophages. A rapid response of Hsp33 to one of these species generated early would therefore be beneficial to the bacterium for rapid protection against oxidative stress. “The superoxide appears to act as a signaling molecule for the bacteria, which further signals oxidative stress,” the research team concludes.

Source:

Journal Reference:

Dirks, T., et al. (2023). Cold atmospheric pressure species generated by plasma, superoxide, singlet oxygen, and atomic oxygen activate the molecular chaperone Hsp33. Journal of the Royal Society Interface, 20(207). doi.org/10.1098/rsif.2023.0300.

bacteria Heat plasma protects protein shock Treatment
bhanuprakash.cg
healthtost
  • Website

Related Posts

AI model detects brain tumors with high precision using epigenetic fingerprints

June 8, 2025

The new study warns long -term risks from germ transplants

June 8, 2025

Self-collection tests could be a solution to increase access to cervical cancer control

June 7, 2025

Leave A Reply Cancel Reply

Don't Miss
Men's Health

30 minutes Kettlebell Core Workouts to strengthen your abdomen

By healthtostJune 9, 20250

Looking to get your basic training at the next level in just 30 minutes? A…

Semaglutide for Weight Loss – Summer Safety and Side Effects Guide

June 9, 2025

Teenagers and sexual education during the Covid-19 pandemic and beyond

June 9, 2025

Creamy all the toast Avocado bagel (easy, salty breakfast!)

June 8, 2025
Stay In Touch
  • Facebook
  • Twitter
  • Pinterest
  • Instagram
  • YouTube
  • Vimeo
TAGS
Baby benefits body brain cancer care Day Diet disease exercise finds Fitness food Guide health healthy heart Life Loss Men mental Natural Nutrition Patients Pregnancy protein research reveals Review risk routine sex sexual Skin study Therapy Tips Top Training Treatment Understanding ways weight women Workout
About Us
About Us

Welcome to HealthTost, your trusted source for breaking health news, expert insights, and wellness inspiration. At HealthTost, we are committed to delivering accurate, timely, and empowering information to help you make informed decisions about your health and well-being.

Latest Articles

30 minutes Kettlebell Core Workouts to strengthen your abdomen

June 9, 2025

Semaglutide for Weight Loss – Summer Safety and Side Effects Guide

June 9, 2025

Teenagers and sexual education during the Covid-19 pandemic and beyond

June 9, 2025
New Comments
    Facebook X (Twitter) Instagram Pinterest
    • About Us
    • Contact Us
    • Privacy Policy
    • Terms and Conditions
    • Disclaimer
    © 2025 HealthTost. All Rights Reserved.

    Type above and press Enter to search. Press Esc to cancel.