Women suffering from endometriosis have an increased risk of premature and early menopause, found both naturally and surgically, the researchers at the University of Queensland.
An integrated international study found that women with endometriosis are 7 times the risk of surgical menopause (including the removal of both ovaries) and at a higher risk of premature menopause (before the age of 40) or early menopause (40-44).
Dr. Hsin-Fang Chung, from UQ School of Public Health; He said that while it was known that endometriosis and treatment could reduce the quality and quantity of eggs, research on its impact on menopause timetable was limited.
We found surgical menopause, on average, 19 months earlier in women with endometriosis, while natural menopause happened 5 months earlier.
Women with endometriosis are twice as likely to experience surgical menopause under 40 years of age, or 1.4 times more likely to have natural menopause before 40. ‘
Dr. Hsin-Fang Chung, UQ’s School of Public Health
Senior writer, Professor Gita Mishra said she was already known early and surgical menopause was associated with negative effects such as cardiovascular disease and premature death.
“Prevention or management of early or medical menopause requires a comprehensive understanding of the underlying causes and preventive measures to address the long -term health risks associated with it,” Professor Mishra said.
The study – which analyzed data from nearly 280,000 women in Australia, the United Kingdom, Sweden and Japan between 1996 and 2022 – is the largest to examine the type and timing of menopause in women with endometriosis.
Research is part of Interlace, an international cooperation that examines women’s reproductive health and chronic illness during their lifetime.
Endometriosis is a chronic and often weakening inflammatory disease, which affects 1 in 7 Australia women, where the tissue similar to the lining of the uterus develops in other parts of the body.
Dr. Chung said he hopes that the evidence would update the updates of the endometriosis management guidelines, emphasizing the importance of long -term monitoring of the situation.
“Women with endometriosis should know that they may be at increased risk of premature or induced menopause, regularly visit their GP to control the risk factors of chronic diseases and focus on prevention strategies,” he said.
The next step of Dr. Chung is to investigate the impact of endometriosis on long -term risks of chronic diseases.
The findings will be presented at the 16th World Conference on Endometriosis in Sydney later this month.
THE The survey is published in Human reproduction.
Source:
Magazine report:
Chung, H.-F., et al. (2025). Connection between endometriosis and type and age of menopause: a aggregate analysis of 279 948 women from five coach studies. Human reproduction. doi.org/10.1093/humrep/deaf068.
