The supply of raspberry dust to infants during the transition to solid foods has shown many promising results in the diversity of guts, highlighting a possible new strategy to support lifelong health.
Study: The introduction of raspberry dust as one of the first supplementary foods changes the composition of germs of the bowel and diversity in infants with human milk: a double blind, randomized controlled test. Credit Picture: Radowitz / Shutterstock
In a recent study published in the magazine Borders in dietResearchers in the United States investigated the impact of the daily intake of raspberry dust on complementary feeding on the development of guts.
Complementary feeding, that is, the transition from wet diets to solid foods usually begins about six months. It is a crucial phase of infants’ development, characterized by rapid changes in nutrient needs and nutritional intake. This dynamic phase is also vital to the formation of the composition of the gut, which is sensitive to configuration and immature in infancy.
The manipulation of early bowel germs could affect the growth of the immune system, the dangers of diseases and the long -term health effects. Therefore, supplemental feeding represents a suitable time to promote a healthier growth of germs. While the diet affects the germic intestine in adults, how these supplementary foods affect the growth of bowel germs is unclear.
For the study
In the present study, the researchers evaluated the effects of raspberry dust as one of the first supplementary foods on the development of the gut in infants. This randomized, placebo -controlled test included infants with full -born human milk, minimal previous supplementary food exposure and previous exposure to antibiotics. Participants were randomized in the raspberry or placebo group.
During the initial visit to the research facility (five or six months old), participants’ carers completed a questionnaire for family and nutrition, demographics, height and weight of the parents, the drugs during pregnancy Basic demographic analyzes have shown statistically significant differences between groups in income and nationality.
Anthropometric measurements of infants and stools and blood samples were also collected at the start. Home visits to seven, nine and 11 months included infant sampling collections, anthropometric measurements and health and allergy questionnaires. The basic procedures were repeated on the final visit to the research unit at 12 months. At each visit, the participants received packages of their assigned dust.
The oblique raspberry powder dried by cooling, equivalent to about two ounces of raspberry, is provided to the raspberry group. The placebo group received isocephalous dust. The powder was powered as a puree formed when mixed with liquid. Carers were asked to provide a package daily from the original price in 12 months and complete a daily introduction calendar. In addition, the carers completed the three -day nutrition files before each visit.
The stool samples were used for intestinal microbial profile with a wide range of reinforcement and sequence 16s rrna genes. The z-scores were calculated for the length of the infants, the weight and the periphery of the head using the standard Health Organization Growth Chart. Chi-Square and independent T tests were used to compare the scores and demographics of participants’ development. Models of linear mixed results were used to analyze germs with exploratory analyzes qualified to p = 0.1 and adapted to the way of delivery and sequence batch.
Findings
In total, 61 participants, 31 in the placebo group and 30 in the raspberry team, completed the study. About 70% of infants did not hire form from birth to registration, and between those with a formula exposure before registration, were less than a week for 70%. The percentage of infants receiving human milk during the study did not differ between the groups.
There were no significant differences between the groups in energy, fiber and macronutrients based on solid foods and study powders. Human milk and formula were excluded from designing analyzes. In 12 months, more infants in the raspberry group consumed the formula than in the placebo group. However, this difference was not statistically significant. The type of recruitment volume was no different between the groups.
On each visit, length for age (Sausage), weight for length, weight for age (Flap) and the periphery of the head for the age of Z-Scores was not significantly different between the groups. While Sausage It was bigger in the raspberry team in seven months, the difference does not remain on subsequent visits. Throughout the group, Flap and Sausage remained under population average throughout the study, with average basic rates of Sausage = -0.96 and Flap = -0.49. Specifically, participants showed lower than the median population Sausage and Flap Throughout the study.
The method of delivery and the batch of sequence were significantly associated with the composition of the germ base line. Alpha and beta diversity measures have shown significant changes over time. Alpha’s three diversity indicators: Shannon’s diversity, smoothness and wealth have increased with age in both groups. The terms of the group × age tend to the greatest variety of alpha in the raspberry group (P ≈ 0.085-0.087), while beta diversity has not shown a significant group effect.
The raspberry group showed increased abundance Decimalist; FlavoniteVeillonaceae, and Buttercin Over time compared to the placebo group. In contrast, four taxonomic shows reduced abundance in the raspberry group over time: Robot; Rays; Stubbornness; Streptococcus. They represented the trends over time. only Rays showed a FDR-valued P-Value Trending to the meaning (0.056).
Or said that the adhesion to eating packages was lower in raspberry compared to the placebo group at 11 and 12 months, which may have weakened detectable results.
Conclusions
Overall, the introduction of raspberry dust as one of the first supplementary foods can exert adding benefits to the growth of germs of the bowel in infants. The diversity of the germ in the gut has increased over time in both groups. However, the raspberry diet tends to increase the diversity of alpha more than the diet of the placebo, although the findings were exploratory.
The basic restrictions include the relatively small size of the sample, the uncontrolled nutritional intake beyond the dust of the study, the inability to quantify human milk intake, the demographic imbalances of the base and the lack of long -term monitoring to evaluate health results.
Test registration: NCT05006989. Financing: National Institute of Diabetes and Digestive and Kidney Diseases and the US Raspberry Council Highbush.
