Close Menu
Healthtost
  • News
  • Mental Health
  • Men’s Health
  • Women’s Health
  • Skin Care
  • Sexual Health
  • Pregnancy
  • Nutrition
  • Fitness
What's Hot

Probiotics of Multiple Executives for Bowel, Skin and Energy Support

July 23, 2025

My healthy stack of sleep: what I use for deep, restorative rest

July 23, 2025

Targeting of tumor cell stem can keep the key to treating colon cancer more effectively

July 23, 2025
Facebook X (Twitter) Instagram
  • About Us
  • Contact Us
  • Privacy Policy
  • Terms and Conditions
  • Disclaimer
Facebook X (Twitter) Instagram
Healthtost
SUBSCRIBE
  • News

    Targeting of tumor cell stem can keep the key to treating colon cancer more effectively

    July 23, 2025

    Aging skin buckles under pressure leading to wrinkles

    July 22, 2025

    Toti-n-seq breakthrough allows the universal and escalating profile of a cell

    July 22, 2025

    Early use of smartphone connected to poorer mental health in young adults

    July 21, 2025

    Creatine exceeds the list as researchers revise new ways to combat osteosarpopenia

    July 21, 2025
  • Mental Health

    How mothers who support mothers can help cover the lack of healthcare and other barriers to care

    July 22, 2025

    Do you have to trust a AI mental health application? -Poic details, privacy risks and 7 -point security checklist

    July 19, 2025

    3 ways Canadians can take control of their finances in a time of economic uncertainty

    July 18, 2025

    Exercise can significantly benefit the mental health of adolescents – here they say the items

    July 13, 2025

    Awareness Month for Mental Health 2025: Turn awareness into action

    July 9, 2025
  • Men’s Health

    30 minutes of full body workout to burn fat and enhance strength

    July 23, 2025

    Erythritol changes brain function and may increase the risk of stroke

    July 21, 2025

    Cardio vs. Training Power: Which is better for shrinking medium -age fat?

    July 21, 2025

    New peak health technologies for all men over 40

    July 20, 2025

    Because I care about men’s health … and why should you also – talking about men’s health

    July 19, 2025
  • Women’s Health

    Probiotics of Multiple Executives for Bowel, Skin and Energy Support

    July 23, 2025

    Power beyond the game: Vicky Fleetwood

    July 22, 2025

    Can you get magnesium with multivitamins and other vitamins?

    July 21, 2025

    I wasn’t tired. I was in heart failure.

    July 20, 2025

    These lamps cause migraines, anxiety and even cancer. That’s you

    July 19, 2025
  • Skin Care

    The bridal flash guide with Joanna Vargas

    July 22, 2025

    Think that your sunscreen protects you? New study probably says no

    July 21, 2025

    Your Guide to Resources: both large and small

    July 20, 2025

    Chocolate causes acne? | Eminence organic skin care

    July 19, 2025

    Itching, irritated, angry scalp? Try this

    July 14, 2025
  • Sexual Health

    How to try HIV in Australia: Free, Fast and Private

    July 21, 2025

    Do orgasms change over time?

    July 21, 2025

    7 gender myths collapsing by a special fertility for couples

    July 19, 2025

    New Jersey’s ban on book bans

    July 18, 2025

    I’m Trans Teen. The US government is attacking my community.

    July 18, 2025
  • Pregnancy

    Restore your week with these Storms-Rose Stork

    July 22, 2025

    Why French baby names tend to modern mothers

    July 21, 2025

    Last minute baby gifts that still join each mom

    July 17, 2025

    How to avoid activation and manage it?

    July 16, 2025

    Cortisol connection – pink stork

    July 15, 2025
  • Nutrition

    Episode 007: The Power of Critical Thinking: Why Success requires Brave Options with Sean Croxton

    July 22, 2025

    Do you need a glucose screen if you don’t have diabetes?

    July 22, 2025

    Do you have a dessert? Here is 5 natural GLP-1 foods for dessert

    July 21, 2025

    Grammie + Pea Camp 2025 • Kath eats

    July 20, 2025

    How to stop grazing and snacks all day (without feeling limited)

    July 19, 2025
  • Fitness

    My healthy stack of sleep: what I use for deep, restorative rest

    July 23, 2025

    New Dumbbell training for beginners (plus my favorite exercises 💪)

    July 22, 2025

    10 healthy ways to launch steam

    July 22, 2025

    10 high -protein breakfast ideas for weight loss

    July 21, 2025

    Homeopathy for varicose veins: what really works

    July 21, 2025
Healthtost
Home»News»Study reveals key antioxidant differences and health benefits
News

Study reveals key antioxidant differences and health benefits

healthtostBy healthtostJanuary 19, 2025No Comments5 Mins Read
Facebook Twitter Pinterest LinkedIn Tumblr Reddit WhatsApp Email
Study Reveals Key Antioxidant Differences And Health Benefits
Share
Facebook Twitter LinkedIn Pinterest WhatsApp Email

Scientists show how Manuka and Ohia Lehua honey differ in their antioxidant potential, showing that while Manuka honey has a higher phenolic content, Ohia Lehua honey excels at reducing oxidative stress and promoting antioxidant defenses.

Study: Phytochemical composition and antioxidant activity of Manuka honey and Ohia Lehua honey. Image credit: Valentyn Volkov / Shuttersotck.com

The use of honey as medicine is widespread in all cultures, mainly due to its antioxidant and anti-inflammatory properties, which protect tissues from oxidative stress. A recent study published in the journal Nutrients investigated the various components of Manuka honey (MH) and ohia lehua honey (OLH) that contribute to their anti-inflammatory properties.

The destructive effects of oxidative stress

Oxidative stress results from an imbalance between reactive oxygen species (ROS) and the body’s antioxidant defenses. During the inflammatory response to injury or infection, immune cells such as macrophages and neutrophils release ROS.

Excess ROS can oxidize and damage cellular proteins, lipids, and nucleic acids, subsequently triggering a cycle of immune inflammatory responses. Unlike acute inflammation, which is the basis of healing, long-term inflammation enhances tissue damage and contributes to chronic disease.

Inflammatory pathways such as nuclear factor kappa B (NF-κB), cyclooxygenase (COX) and mitogen-activated protein kinase (MAPK) lead to the increased production of pro-inflammatory cytokines such as interleukin-6 (IL-6). These cytokines induce inflammation, oxidative stress and the activation of the NLRP3 inflammasome. NLRP3 increases inflammation and can cause chronic inflammatory conditions such as type 2 diabetes and atherosclerosis.

The ingredients of honey

Honey is a natural product consisting mainly of fructose, glucose and water. It also contains many phenolic plant compounds, enzymes and organic acids, as well as hydrogen peroxide (H2THE2) and methylglyoxal (MG), which are both bioactive compounds.

Honey is a traditional medicine used to reduce inflammation and oxidative stress. Its antioxidant properties are essential for the prevention of cardiovascular risk factors, diseases and cancer.

MH is pure honey produced by bees in New Zealand that feed mainly on the Manuka bush (Leptospermum scoparium), while OLH honey is produced in the Ka’u area of ​​the Big Island of Hawaii from bees that feed on Metrosiderospolymorpha flowers.

Both MH honey and Kanuka honey inhibit inflammation in immune and cancer cell cultures. The phenolic acids and flavonoids of honey also have an antioxidant effect.

Previous studies have proven that honey can inhibit bacteria that are resistant to many drugs such as Staphylococcus aureus and Pseudomonas aeruginosa. With its high sugar concentrations, acidic pH and bioactive content, honey prevents microbial growth and wound infection and promotes tissue repair.

Antimicrobial mechanisms in honey are either peroxide or non-peroxide based. Peroxide-based honey converts glucose to gluconic acid and hydrogen peroxide via glucose oxidase. In comparison, peroxide-free honey, such as MH, relies on polyphenols and the formation of methylglyoxal, which suppresses glucose peroxidase activity.

About the study

The current study examined the composition of MH and OLH, particularly the concentrations of polyphenolic plant compounds present in these types of honey. Additional in vitro Experiments were performed to evaluate their antioxidant activity by determining the free radical scavenging capacity of the extracts.

The current study performed several in vitro assays, including ferric ion-reducing antioxidant power (FRAP), 1,1-diphenyl-2-picrylhydrazyl (DPPH), and H2THE2 and nitric oxide (NO) scavenging tests. Trolox, a synthetic analogue of vitamin E, has also been used to measure the antioxidant capacity of foods, beverages and supplements.

In vivo The tests looked at total oxidative stress (TOS), total antioxidant capacity (TAC) and the oxidative stress index (OSI), which reflects the ratio between TOS and TAC in a rat model of inflammation. Levels of advanced protein oxidation products (AOPP), total thiols, malondialdehyde (MDA), which indicates levels of lipid peroxidation, and NO, an endothelial, nerve, and immune-derived signaling molecule, were also measured. in vivo.

Phenolic profile

MH had ten times the phenolic content of OLH. Both honey products contained a wide range of phenolic compounds, with nonflavonoids such as hydroxybenzoic acid accounting for approximately 90% and 68% of phenolics such as 2,4-dihydroxybenzoic acid and gallic acid in MH and OLH, respectively .

Flavonoids include anti-inflammatory and free radical-scavenging apigenin glycoside, quercetin glycoside and quercetin, all of which were present only in MH. Pinocembrin-glucoside was present in both MH and OLH.

Antioxidant properties

OLH was high in vivo antioxidant activity, which is mainly achieved by reducing the oxidative activity of the serum. In addition, OLH reduced TOS, OSI and MDA more than diclofenac, a non-steroidal anti-inflammatory drug (NSAID), in addition to increasing TAC and SH.

OLH prevents lipid peroxidation, reduces oxidative stress, and increases antioxidant capacity rather than inhibiting NO and protein oxidation pathways. At the lower OLH concentration, the antioxidant activity was greater. In contrast, TOS and OSI inhibition was more potent at higher dilutions while exceeding the observed effects of diclofenac.

MH showed limited antioxidant activity at all dilutions compared to its strong antibacterial activity. MH reduced NO and AOPP and increased SH levels, surpassing the effects of diclofenac.

TOS and OSI decreased moderately. Higher dilutions were less effective than diclofenac or Trolox. In particular, the composition and concentration of phenolic compounds in MH is variable, which can change its antioxidant properties.

Syringic acid inhibits pro-inflammatory pathways and scavenges free radicals. MH is high in methyl-syringic acid, which protects DNA from oxidative damage.

conclusions

MH was associated with a tenfold higher phenolic content than OLH, attributed to its antioxidant capacity. However, these effects are concentration dependent. Conversely, OLH significantly reduces oxidative stress by scavenging free radicals and increases serum antioxidant capacity.

Honey is an essential and traditional functional food. Therefore, the components present in honey should be identified and investigated for their possible effect on human health. Such natural foods should be explored as promising sources of dietary antioxidant activity.

Journal Reference:

  • Morar, II, Pop, RM, Peitzner, E., et al. (2025). Phytochemical composition and antioxidant activity of Manuka honey and Ohia Lehua honey. Nutrients. doi:10.3390/nu17020276.
antioxidant benefits differences health key reveals study
bhanuprakash.cg
healthtost
  • Website

Related Posts

Targeting of tumor cell stem can keep the key to treating colon cancer more effectively

July 23, 2025

Aging skin buckles under pressure leading to wrinkles

July 22, 2025

Toti-n-seq breakthrough allows the universal and escalating profile of a cell

July 22, 2025

Leave A Reply Cancel Reply

Don't Miss
Women's Health

Probiotics of Multiple Executives for Bowel, Skin and Energy Support

By healthtostJuly 23, 20250

Submitted by Metagenics Marketing Team The intestine makes you more than helping with digestion -…

My healthy stack of sleep: what I use for deep, restorative rest

July 23, 2025

Targeting of tumor cell stem can keep the key to treating colon cancer more effectively

July 23, 2025

30 minutes of full body workout to burn fat and enhance strength

July 23, 2025
Stay In Touch
  • Facebook
  • Twitter
  • Pinterest
  • Instagram
  • YouTube
  • Vimeo
TAGS
Baby benefits body brain cancer care Day Diet disease exercise finds Fitness food Guide health healthy heart Improve Life Loss Men mental Natural Nutrition Patients Pregnancy protein research reveals Review risk routine sex sexual Skin study Therapy Tips Top Training Treatment ways weight women Workout
About Us
About Us

Welcome to HealthTost, your trusted source for breaking health news, expert insights, and wellness inspiration. At HealthTost, we are committed to delivering accurate, timely, and empowering information to help you make informed decisions about your health and well-being.

Latest Articles

Probiotics of Multiple Executives for Bowel, Skin and Energy Support

July 23, 2025

My healthy stack of sleep: what I use for deep, restorative rest

July 23, 2025

Targeting of tumor cell stem can keep the key to treating colon cancer more effectively

July 23, 2025
New Comments
    Facebook X (Twitter) Instagram Pinterest
    • About Us
    • Contact Us
    • Privacy Policy
    • Terms and Conditions
    • Disclaimer
    © 2025 HealthTost. All Rights Reserved.

    Type above and press Enter to search. Press Esc to cancel.