Written by Allison Goins, Ph.D. | Posted on February 8th2025 At 6:00 am
Have you ever wondered why your skin seems to grow faster when you are constantly in the sun or exposed to pollution? The culprit: free roots. These tiny, unstable molecules cause diversification to your skin. They are responsible for accelerating aging, causing coloring issues and even contributing to skin diseases. But don’t worry – Science has answers. Let’s break how the relationship between free radicals and skin, what research says and how to protect yourself with the right skin care ingredients.
Understanding the relationship between free radicals and skin health is vital to protection from premature aging.
Free radicals are like the tiny, unstable turmoil. They are missing molecules called electrons. Because they are missing from these pieces, they always look for other molecules to get. This creates a chain reaction, like a falling domino, where one molecule steals an electron from another, and then this molecule tries to steal one from something else and just continues to happen.
This electron theft spree is called oxidative stress and is not good for your skin. It can damage important things such as collagen and elastin, which keep your skin firm and elastic. It may even harm your DNA, which is like the instructions for your cells.
Related post: How to regain elasticity in the skin: an important step in anti-aging skin care
Your body makes some free radicals of course, but things in the environment can cause your body to do more. These bad guys include UV rays from the sun, infrared and pollution. Scientists believe that just out in the sun can cause up to 80% of the external aging of the skin.
Free radicals and skin aging are linked. These riot molecules can cause wrinkles and other signs to become premature.
Your skin has some natural defenses from free radicals. These natural defenses are called antioxidants. Antioxidants such as vitamins E, C and A help protect your skin from free radicals. Melanin is another of the natural defenses of your body against antioxidants.
Related post: Antioxidants in skin care, what are they and what are they doing?

Free radicals and skin do not take together! When free radicals flood the natural defenses of the skin, they cause oxidative stress and can cause many problems:
Wrinkles and fine lines: Free radicals are like tiny bullying that break down collagen and elastin. These are the things that make your skin firm and elastic. When destroyed, you take wrinkles and fine lines.
Coloring Issues: Sometimes free radicals make your skin produce too much melanin. Melanin is what gives your skin its color. Excessive melanin at one point can cause dark spots and make your skin tone heterogeneous. Thus, free radicals and skin tone can be attached.
Inflammation and sensitivity: Free radicals can also cause inflammation, which is when your skin is red and irritated. This can make skin problems such as acne, eczema and rosacea. Free radicals and skin sensitivity definitely go together.
Increased risk of skin cancer: Finally, free radicals can damage your DNA, which is like the instruction manual for your cells. This damage can sometimes lead to skin cancer. Thus, protecting your skin from free radicals is really important for healthy skin.
However, not all free radicals are for your skin.
Some free radicals act as signaling molecules, helping the skin adapt to stress and repair itself. But when their levels become too high – thanks for excessive exposure to the sun, pollution or bad lifestyle habits – the damage goes beyond the benefits.

Protection of your skin from free radicals: What do you need to know about free radicals and skin
Now that we know that free radicals are inevitable, how can we fight? The answer: Antioxidants and protective treatment of the skin.
Sunscreen: Your first line of defense
UV radiation is one of the largest culprits behind the formation of free radicals. A sunscreen wide spectrum (SPF 30 or higher) helps to involve UVB and UVA rays, reducing free radical damage. However, research shows that only sunscreen is not always enough-it does not completely protect against the free radicals caused by UVA. There the antioxidants come in.
Antioxidants: The Final Fighters of Free Root
Antioxidants neutralize free radicals, donating an electron, stopping oxidative stress before they destroy the skin cells. Some of the best antioxidants in skin care include:
- Vitamin C: An antioxidant of energy production that illuminates the skin, the tone of spreading and stimulates collagen production. It also enhances the effectiveness of sunscreen.
- Vitamin E: It works in parallel with vitamin C to protect against ultraviolet damage while moisturizing the skin.
- Carotenoids (beta-carotene, lycopene): It is found in some skin care products, these antioxidants interact with free radicals to reduce oxidative stress.
- Niasinamide (Vitamin B3): It helps reduce inflammation and enhances the barrier of the skin against environmental stressors.
Do skin care products really work with antioxidants?

Many skin care brands claim that their products “neutralize free radicals” or “reverse aging of the skin”. But do they?
Science supports the use of local antioxidants, but not all antioxidants are created equal. To be effective, it must be:
✔ Constant: Antioxidants such as Vitamin C can quickly deteriorate when exposed to light and air. Look for serums in opaque, airtight packaging.
✔ Properly configured: The right combinations of PH and ingredients (such as vitamin C + vitamin E + ferulic acid) enhance stability and efficacy.
✔ Used consistently: Antioxidants do not work overnight – the accommodation is decisive.
Finally, understanding the harmful effects of free radicals and skin health is vital to maintaining a youthful and vibrant complexion
Free radicals play an important role in aging and skin damage, but you do not have to surrender to them. A compact skin care routine – including sunscreen and antioxidants – can help minimize their results. As the research continues, skin care products will probably become even more effective in preventing and repairing oxidative stress.
So, the next time you apply your vitamin C serum or sunscreen, you know that you give your skin the defense it needs against these tiny but powerful attackers.
References
Darvin, Me, & Lademann, J. (2010). Formation of free radicals on human skin during radiation with infrared light. Journal of Research Dermatology; 130(7), 1831-1837.
Darvin, Me, Lademann, J., Altmeyer, P., & Sterry, W. (2007). In vivo spectroscopic Raman analysis of the effect of IR radiation on antioxidants of carotenoid beta-carotene and lycopene on human skin. Formation of free radicals. Biology and free radical medicines; 43(4), 542-550.
Haywood, RM, L., M., W., J., & D. (2003). Sunscreen that protect insufficiently from free radicals caused by UV AA on the skin: effects on aging of the skin and melanoma? Journal of Research Dermatology; 121(6), 1416-1422.
Jackson, MJ (1999). Free Roots on the skin and muscles: devastating agents or signals to adapt? European Dermatology Magazine; 9(1), 5-11.
Jurkiewicz, NE, & Buettner, GR (1996). Detection EPR Free Roots on Radiated Skin with UV Radiation: Mouse against Humans. Photochemistry and Photoviology; 64(6), 954-958.
Keshari, A., Kumar, A., Singh, P., & Gupta, R. (2016). The cleansing property and protective property of its protein root Sacred (LARGE). Journal of Pharmacy Research; 10(6), 149-154.
Lademann, J., Darvin, Me, Wiegrebe, W., Schlumpberger, M., & Sterry, W. (2011). Interaction between carotenoids and free radicals on human skin. Experimental dermatology; 20(1), 78-80.
Nakai, Y, & Tsuruta, D. (2021). What are the reactive types of oxygen, free radicals and oxidative stress in skin diseases; Newspaper of dermatological science; 100(1), 20-25.
Poljšak, B., & Dahmane, R. (2012). Free radicals and exogenous aging of the skin. Research and practice of dermatology; 2012135206.