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Home»Skin Care»Injections of Polynucleotide: Hype or Holy Grail, a complete scientific guide supported by science
Skin Care

Injections of Polynucleotide: Hype or Holy Grail, a complete scientific guide supported by science

healthtostBy healthtostFebruary 23, 2025No Comments9 Mins Read
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Injections Of Polynucleotide: Hype Or Holy Grail, A Complete Scientific
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There are new skin care ingredients and treatments that promise to be a miracle of youth elixir every year. This year, polynucleotide injections or salmon sperm injections are the treatment of skin care. So let’s discuss these injections of polynucleotides! Is the real agreement or just another fleeting tendency to care for the skin? These treatments use molecules derived from fish DNA (tips where the sperm sperm comes). They have a lot of buzz for their ability to commercially rejuvenate your skin completely.

The science behind these injections is interesting. However, like any new trend, it is worth a healthy dose of skepticism. Especially before running on a provider’s office and drop hundreds of dollars. This article examines the evidence. He explains how polynucleotides work (or if they work!). It also weighs the good and bad spots. This will help you decide if this treatment is worth it.

What are polynucleotides and how do they benefit the skin?

Polynucleotides are tiny nucleotide chains. Nucleotides are the fundamental structural elements of DNA. Are the instructions for cells in your body. Are similar to peptides and extracurricular. Scientists want to use them to create remedies and products against aging.

Specifically on your skin, They emphasize natural skin repair processes by enhancing cellular growth, increasing hydration and reducing inflammation. They also help make more collagen, which keeps the skin steady and young. But do they work when they were injected?

Injections of Polynucleotides: What to expect

Your skin has a barrier. It excludes bad things like pollution. Unfortunately, it also blocks good things, such as useful ingredients. Injections bypass this barrier. They provide anti -aging ingredients directly to the dermis. This is where they need the most. Injections of polynucleotides work in the same way. Have been injected into the skin. This allows for targeted application. It also maximizes the benefits. These injections are marketed to deal with many skin worries. These include wrinkles, skin relaxation, dryness, redness and uneven texture.

So where do the name Salmon Salmon SPERM Brensions come from or the sperm of salmon?

Polynucleotide treatments are sometimes called “salmon sperm injections” or “facial salmon sperm”. The name comes from the source of the polynucleotides. They are taken from the DNA fish, specifically the salmon sperm. The most common type is very cleaned polynucleotides (PN-HPT ™). Injections are commercially available to rejuvenate the skin. They enhance hydration, improve elasticity and reduce redness. This makes them such a popular treatment against aging. But don’t worry! Injections do not really contain living sperm. Contain only cleaned DNA fragments. These help the skin to heal and renew.

So now science … injections of polynucleotides: What real results can you expect

Is polynucleotide injections an effective anti -aging treatment? The answer is yes! Salmon sperm injections are much more widespread in South Korea. Clinical trials and research studies with providers offered by this service in their clinics have shown that polynucleotide injections can significantly improve skin smoothness, stability and hydration. They can effectively reduce wrinkles, especially fine lines. While they may not delete fully deep wrinkles, they offer a remarkable improvement in skin quality. Polynucleotides also help in steady and tightening the skin by enhancing collagen production, improving elasticity and a more youthful appearance. They are still effective under the eyes, where they can face concerns such as fine lines, dark circles and fine skin.

There is a warning: There is not many elements that evaluate them as an autonomous treatment. In a study, around 230 Korean skinThe walls were asked about the injections of polynucleotides. Nearly 190 they said they were used with other treatments. Injections of polynucleotide were typically used with laser or light treatment, hyaluronic acid or botox -based fillers. This means that it is difficult to say what benefits are directly related to polynucleotide injections. The benefits of their patient could come from other treatment or combination of cooperation to give even better results than they could.

Polynucleotide infusion treatments: What to expect

Most studies say you need three to four injections of polynucleotides for the best results. It is a few weeks to a month. They are often used with other treatments. Some providers recommend maintenance treatments every few months to maintain the results.

Recovering polynucleotide injections is usually fast. Most people recover within two days. You may have swelling or bruising for a few days. There is a minimum of time to break. After the procedure, avoid the sun for two days. Don’t do intense workouts for a day. And do not touch the area that has been treated. It is also best to avoid alcohol for a day. This is because it can make bruises and swelling worse.

The cost varies. It depends on the clinic, product and area treated. You can wait to pay between $ 300 and $ 800 per session. Thus, full treatment could cost between $ 900 and $ 3200.

Risks and side effects of Injection of polynucleotidesmall

Injections of polynucleotide are generally considered safe. However, as is the case with any injectable process, mild side effects are possible. These include edema, redness, bruises and tenderness. Serious problems are rare, but bad injections can lead to problems. It is important to find a specialized provider that will reduce the risks.

Injections of polynucleotides may not be for everyone. They are generally not recommended for pregnant or lactating women, people with fish allergies (due to the nature of PN fish) or people with active skin infections or severe autoimmune situations. Talking to your provider is very important to make sure you are a good candidate for treatment. Currently, polynucleotides are not approved by the FDA in the US. They are used widely in Europe and Asia and have positive security files.

Hectare Are polynucleotide injections better than other common treatments?

New treatments always have a lot of advertising campaign. It is easy to trap in it. But it is important to know the facts. So let’s compare the injections of polynucleotides into other treatments. Your provider knows your skin better. They can give you the best tips. But we can talk about some general differences.

Are polynucleotide injections better than botox?

The answer depends on your goals. Botox freezes the muscles. This prevents wrinkles caused by the muscles that move. Polynucleotides Rejuvenate your skin. They take skin cells to produce more collagen and other proteins. Both can help with aging. But they work in different ways.

What about polynucleotide injections compared to fillers?

Again, it depends. Payments add tension. Wrinkles were flooded and filled the hollow areas immediately. Polynucleotides need time to work. They tell your cells to make more collagen. That is why you need a series of injections. So you have the full benefits. Hydration, tightening and normalization. Again, both fight the signs of aging. But they do it differently. They operate in complementary ways. That is why many providers use them together.

After all, there is no “better” treatment. It depends on your needs and goals.

Final thoughts on injections of polynucleotides

Injections of polynucleotides can help fight aging points. They can rejuvenate your skin. They can also moisturize, tighten and improve the texture of the skin. He is not a replacement for botox or fillers. But they can be a good addition to your routine. If you are interested, talk to a skin professional. They can help you decide if this treatment is appropriate for you.

References

Arakos AAraco F, Raichi M. Clinical Effectiveness and Safety of Polynucleotides (PN-HPT®) and Cross Hyaluronic Acid for moderate to severe ritholate folds: a perspective, randomized exploratory study. J Cosmet Dermatol. 2023 Jan 22 (1): 146-155. DOI: 10.1111/JOCD.15064. EPUB 2022 May 26. PMID: 35531796; PMCID: PMC10084116.

Cavallini m, Bartoletti E, Maioli L, Massirone A, Pia Palmieri I, Papagni M, Priori M, Trocchi G, as members of Polynucleotides Hpt ™ Priming Board, Collegio Italiano Delle Società Scientifiche di Medicina Estetica of aesthetic medical scientific companies) – SIME, Agorà, sies. Consensus report on the use of PN-HPT ™ (Polynucleotides of High Cleanled Technology) in aesthetic medicine. J Cosmet Dermatol. March 2021 20 (3): 922-928. DOI: 10.1111/JOCD.13679. EPUB 2020 Sep 21. PMID: 32799391; PMCID: PMC7984045.

Lampridou sBassett S, Cavallini M, Christopoulos G. The effectiveness of polynucleotides in aesthetic medicine: a systematic review. J Cosmet Dermatol. 2024 Dec. 8: E16721. DOI: 10.1111/JOCD.16721. Epub in front of printing. PMID: 39645667.

Lee dChoi H, Yoo K, Park Yj, Park HJ, Oh SM, Ji GH, Rah Gc, Shin Dw. Evaluation of current practices and the perceived efficiency of injectable polynucleotide for expanded facial resources between cosmetic doctors: Research -based evaluation. SKIN RES TECHNOL. 2024 SEP, 30 (9): E13738. DOI: 10.1111/srt.13738. PMID: 39233467; PMCID: PMC11375025.

Lee dkOh m, kim mj, oh sm. Clinical effects of polynucleotide with intradermal injections of hyaluronic acid on facial erythosis: Effective redness using polynucleotides. SKIN RES TECHNOL. 2024 Sep 30 (9): E70034. DOI: 10.1111/srt.70034. PMID: 39258788; PMCID: PMC11388635.

Lee D, Kim Mj, Park HJ, Rah Gc, Choi H, Anh St, Ji Gh, Kim Ms, Kim G, Shin Dw, Oh Sm. Current practices and the perceived efficacy of polynucleotides to treat cosmetic doctors. SKIN RES TECHNOL. 2023 SEP, 29 (9): E13466. DOI: 10.1111/srt.13466. PMID: 37753681; PMCID: PMC10485387.

Lee kwaChan Kwl, Lee A, Lee Ch, Wan J, Wong S, Yi Kh. Polynucleotides in Aesthetic Medicine: A review of today’s practices and perceptual efficiency. Int j mol sci. 2024 July 27, 25 (15): 8224. DOI: 10.3390/IJMS25158224. PMID: 39125793; PMCID: PMC11311621.

PortfullyLIEW S, TEE XJ, CHONG I, LO FJ, HO MJ, ONG K, CAVALLINI M. Polynucleotides HPT for Asian skin regeneration and rejuvenation. Clin Cosmet Investig Dermatol. 2024 Feb 13; 17: 417-431. DOI: 10.2147/CCID.S437942. PMID: 38371328; PMCID: PMC10874187.

Park kySeok J, Rho NK, Kim Bj, Kim Long chain polynucleotide information for skin rejuvenation: efficacy and complications in five patients. Dermatol Ther. 2016 Jan-Feb, 29 (1): 37-40. DOI: 10.1111/dth.12299. EPUB 2015 November 2. PMID: 26814448.

Rho nkHan Kh, Cho M, Kim Hs. A study on the cosmetic use of injectable polynucleotide: the model of practice between Korean dermatologists. J Cosmet Dermatol. 2024 Apr 23 (4): 1243-1252. DOI: 10.1111/JOCD.16125. EPUB 2023 Dec 13. PMID: 38093498.

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