If you’re the type of person who likes to try new things and keep up with the latest skincare trends, ampoules may have popped up on your radar. If they haven’t yet, now is the time to find out if they’re right for your skin.
Across Europe, ampoules are a staple in science-backed skincare — recommended in dermatologists’ offices and pharmacies. They are known for their concentrated formulas, elegant presentation and most importantly, their stability.
Let’s take a closer look and find out when, why and how to use ampoules in your skincare routine along with expert advice straight from the source in Barcelona — with Isdinceutics Product Manager Berta Ochoa.
What is a skin care ampoule?
When first using an ampoule in your skin care routine, one important thing to remember is that the word ampoule describes the unique, sealed package containing serum. So the contents are serums while the package is the ampoule. Berta clarifies, “Skin ampoules are also known as serums-in-ampoules.” These serums are usually powerful yet minimalist types, focusing on specific combinations of ingredients to provide your skin with targeted care.
Why is it a great format?
If you’re used to full-size plastic tubes or ceramic jars, small glass ampoules may seem unusual. But their form is one of their greatest advantages. Berta explains, “Since the ampoules are designed to be opened only once, serum formulations don’t have to constantly deal with the elements.”
And what does that mean for your skin? These closed containers skip the need for emulsifiers or stabilizers that larger serum formats may require – allowing for simple results. “Ampoules are like shots of concentrated ingredients that can be easily applied as needed,” says Berta.
“Ampoules are like shots of concentrated ingredients that can be easily applied as needed.”
This is especially true when it comes to a certain brightening super ingredient. Vitamin C is most effective when is kept constant and out of contact with the air around it, avoiding oxidation.

When and where should I use ampoules in my skincare routine?
“If I explain how to use ampoules to a friend (which has happened more than a few times), I always mention them as the perfect choice for skin intervention”, Berta laughs. “A brightness boost? Hydration; It’s a great choice for when your skin needs a little something extra.”
Another advantage of the ampoule: individual vials offer the flexibility to decide when, where and how often to use them. “For me, the format is really practical. If I’m going on a quick trip, I just pack what I need,” she shares.
When thinking about how to add new finds to your skincare routine, it’s a good idea to focus on texture. And remember this rule of thumb: light to heavy. Facial serums are usually water or oil based and are quickly absorbed into the skin. This means it is on the lighter side, and should go into your routine after cleansing but before moisturizing. This helps the concentrated ingredients work properly.

How do I open an ampoule?
Most skin blisters will come with instructions on the box or packaging, so look carefully before opening. Isdinceutics ampoules use the following set of instructions, which you can follow to safely open an ampoule during your daily skin care routine.

1. Shake the ampoule
Gently shake the ampoule to ensure the contents are well mixed. This is especially important for oil-based serums. Gently shake or tap the neck of the ampoule to ensure that the serum inside settles to the bottom of the vial.
2. Break it
To safely open the ampoule, place it in the protective tube. To break the ampoule, push the tube down and pull the bottom of the ampoule away from you.


3. Prepare the vial
Place the special tip of the applicator on the now opened ampoule. Do not dispense the serum without using the tip of the applicator, as the vial is made of sensitive glass. Once the applicator tip is in place, remove the cap and dispense the serum onto your hand or directly onto your face.
4. Apply the serum
Gently massage half the contents of the ampoule into the skin.

How should I apply the serum?
Once you’ve opened the ampoule properly and prepared it, it’s time to apply the serum. Dispense half of the serum into the palm of your hand or onto your face and slowly begin to massage into your skin, over the face and neck, avoiding the eye area. Using gentle circular motions until fully absorbed, enjoy this little moment of self-care — you deserve it!
Then put the cap back on the end of the applicator and store it until the next use. Isdinceutics ampoules should be used within 48 hours of opening so that you can use the same ampoule in your skin care routine the next morning or evening, depending on the type of serum. Berta’s favorite? “Instant Flash. I always use it before big events — whenever I really want to look and feel my best.”

Now that you’ve seen how easy it is to add ampoules to your skincare routine, it’s time to find the perfect formula for your skin’s needs. Find out which serum is best for you.
Report:
Telang PS. Vitamin C in Dermatology. Indian Dermatol Online J. 2013 Apr;4(2):143-6. doi: 10.4103/2229-5178.110593. PMID: 23741676; PMCID: PMC3673383.
Editorial team
Our namesake embodies the spirit of embracing life and all its wonder. As wellness journalists, we explore topics that stimulate the senses and keep curiosity alive. We believe that glowing skin is the result of a healthy body and mind. By connecting beauty with science, we aim to inspire you to live young at every age.